Rabbit Polyclonal Phospho-Stat5a (S780) antibody (STJ90413)

$99.00$319.00

Reactivity: Human, Mouse, Rat
Applications: WB, IHC, IP, ELISA
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

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Rabbit Polyclonal Phospho-Stat5a (S780) antibody (STJ90413)

Supplier: St John’s Laboratory Ltd.

Recommended applications: WB, IHC, IP, ELISA

Recommended dilution: WB 1:500-1:2000; IHC 1:100-1:300; IP 1:200-500; ELISA 1:10000;

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Stat5a (phospho Ser780) Polyclonal Antibody.

Alternative names:

Check alternative names for the antibody

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STAT5A antibody, STAT5 antibody,|MGF antibody|Signal transducer and activator of transcription 5A antibody|Signal Transducer and Activator of Transcription 5B antibody|STA5A_HUMAN antibody|STAT 5A antibody|STAT 5B antibody|STAT5 antibody|STAT5A antibody|STAT5B antibody|Transcription factor STAT5A antibody|Transcription factor STAT5B antibody|Phospho anti-STAT5 (Y694) antibody [E208] (ab32364)
SCBT cat No: sc-81524|sc-12893|sc-101806|sc-81525|sc-136019|sc-101808|sc-11762|

 

Name

Stat5a (phospho Ser780) Polyclonal Antibody

Catalogue No.

STJ90413

Reactivity

Human, Mouse, Rat

Specificity

Phospho-Stat5a (S780) Polyclonal Antibody detects endogenous levels of Stat5a protein only when phosphorylated at S780.

Immunogen

Synthesized phospho-peptide derived from Stat5a (phospho Ser780) at AA range 720-800

Host

Rabbit

Applications

WB, IHC, IP, ELISA

Recommended dilution

WB 1:500-1:2000; IHC 1:100-1:300; IP 1:200-500; ELISA 1:10000;

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

91 kDa

Formulation

Stat5a (phospho Ser780) Antibody was tube-contained. Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration

1 mg/ml

Purification

Stat5a (phospho Ser780) Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Storage

-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

Signal transducer and activator of transcription 5A antibody

Database links

Human UniProt/Swiss-Prot:P42229;Mouse UniPort/Swiss-Prot: P42230;Rat UniProt/Swiss-Port: Q62771;Human Entrez Gene: 6776;Mouse Entrez Gene: 20850;Rat Entrez Gene: Rn.154399

Protein names

Signal transducer and activator of transcription 5A

Protein function

Carries out a dual function: signal transduction and activation of transcription. Mediates cellular responses to the cytokine KITLG/SCF and other growth factors. Mediates cellular responses to ERBB4. May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4. Binds to the GAS element and activates PRL-induced transcription. Regulates the expression of milk proteins during lactation.

Protein sequence and domain

Belongs to the transcription factor STAT family. / Contains 1 SH2 domain.

Protein post-translational modifications

Tyrosine phosphorylated in response to KITLG/SCF, IL2, IL3, IL7, IL15, CSF2/GMCSF, GH1, PRL, EPO and THPO. Activated KIT promotes phosphorylation on tyrosine residues and subsequent translocation to the nucleus. Tyrosine phosphorylated in response to constitutively activated FGFR1, FGFR2, FGFR3 and FGFR4. Tyrosine phosphorylation is required for DNA-binding activity and dimerization. Serine phosphorylation is also required for maximal transcriptional activity (By similarity). Tyrosine phosphorylated in response to signaling via activated FLT3; wild-type FLT3 results in much weaker phosphorylation than constitutively activated mutant FLT3. Alternatively, can be phosphorylated by JAK2 at Tyr-694. Dephosphorylation on tyrosine residues by PTPN2 negatively regulates prolactin signaling pathway. / ISGylated.

Protein cellular localization

Cytoplasm / Nucleus

Research area

All research areas>Transcription Regulators>Stat
(View all antibody categories related to Transcription Regulators)

Note

AntibodyPlus can customize Stat5a (phospho Ser780) Antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

St John’s Laboratory Ltd.

Product type

Primary antibody

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