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Rabbit Polyclonal Phospho-Stat5a/b (S726/731) antibody (STJ91088)
Supplier: St John’s Laboratory Ltd.
Recommended applications: WB, IHC, IF, ELISA
Recommended dilution: WB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:20000;
Recommended protocols: check protocols
Click or hover above images to see image description for Stat5a/b (phospho Ser726/731) Polyclonal Antibody.
Check alternative names for the antibodyExpand
STAT5A antibody, STAT5 antibody,|MGF antibody|Signal transducer and activator of transcription 5A antibody|Signal Transducer and Activator of Transcription 5B antibody|STA5A_HUMAN antibody|STAT 5A antibody|STAT 5B antibody|STAT5 antibody|STAT5A antibody|STAT5B antibody|Transcription factor STAT5A antibody|Transcription factor STAT5B antibody|Phospho anti-STAT5 (Y694) antibody [E208] (ab32364)
SCBT cat No: sc-81524|sc-12893|sc-101806|sc-81525|sc-136019|sc-101808|sc-11762|
Stat5a/b (phospho Ser726/731) Polyclonal Antibody
|Catalogue No.|| |
Human, Mouse, Rat
Phospho-Stat5a/b (S726/731) Polyclonal Antibody detects endogenous levels of Stat5a/b protein only when phosphorylated at S726/731.
Synthesized phospho-peptide derived from Stat5a/b (phospho Ser726/731) at AA range 660-740
WB, IHC, IF, ELISA
|Recommended dilution|| |
WB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:20000;
|Molecular weight|| |
Stat5a/b (phospho Ser726/731) Antibody was tube-contained. Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Stat5a/b (phospho Ser726/731) Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-20 Celsius degree. Avoid repeated freeze/thaw cycles.
|Alternative antibody names|| |
Signal transducer and activator of transcription 5A antibody
|Protein names|| |
Signal transducer and activator of transcription 5A
|Protein function|| |
Carries out a dual function: signal transduction and activation of transcription. Mediates cellular responses to the cytokine KITLG/SCF and other growth factors. Mediates cellular responses to ERBB4. May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4. Binds to the GAS element and activates PRL-induced transcription. Regulates the expression of milk proteins during lactation.
|Protein sequence and domain|| |
Belongs to the transcription factor STAT family. / Contains 1 SH2 domain.
|Protein post-translational modifications|| |
Tyrosine phosphorylated in response to KITLG/SCF, IL2, IL3, IL7, IL15, CSF2/GMCSF, GH1, PRL, EPO and THPO. Activated KIT promotes phosphorylation on tyrosine residues and subsequent translocation to the nucleus. Tyrosine phosphorylated in response to constitutively activated FGFR1, FGFR2, FGFR3 and FGFR4. Tyrosine phosphorylation is required for DNA-binding activity and dimerization. Serine phosphorylation is also required for maximal transcriptional activity (By similarity). Tyrosine phosphorylated in response to signaling via activated FLT3; wild-type FLT3 results in much weaker phosphorylation than constitutively activated mutant FLT3. Alternatively, can be phosphorylated by JAK2 at Tyr-694. Dephosphorylation on tyrosine residues by PTPN2 negatively regulates prolactin signaling pathway. / ISGylated.
|Protein cellular localization|| |
Cytoplasm / Nucleus
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St John’s Laboratory Ltd.
|Product type|| |
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