Rabbit Polyclonal Phospho-STAT6-Y641 antibody (AP0456)

$99.00$259.00

Reactivity: Human
Applications: WB,IHC
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit Polyclonal Phospho-STAT6-Y641 antibody (AP0456)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC

Recommended dilution:

WB 1:500 – 1:2000
IHC 1:50 – 1:100

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit Polyclonal Phospho-STAT6-Y641 antibody.

Alternative names:

Check alternative names for the antibody

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STAT6B antibody; STAT6C antibody; D12S1644 antibody; IL-4-STAT antibody;
12S1644 antibody|D12S1644 antibody|IL 4 STAT antibody|IL-4 Stat antibody|IL4 STAT antibody|Interleukin 4 Induced antibody|Interleukin 4 Induced Transcription Factor IL4 STAT antibody|Signal transducer and activator of transcription 6 antibody|Signal Transducer And Activator Of Transcription 6 Interleukin 4 Induced antibody|Signal Transducer And Activator Of Transcription 6 Nirs Variant 1 antibody|Signal transducer and activator of transcription 6, interleukin 4 induced antibody|STAT 6 antibody|STAT interleukin4 induced antibody|STAT, interleukin4 induced antibody|Stat6 antibody|STAT6_HUMAN antibody|STAT6B antibody|STAT6C antibody|Transcription factor IL 4 STAT antibody|Anti-STAT6 antibody [YE361] (ab32520)

SCBT cat No: sc-81525|sc-136019|sc-101808|sc-11762|sc-373991|sc-390727|sc-135221|sc-104630|sc-83014|sc-83015|sc-23758|sc-325227|sc-12913|sc-16852|

Name

Rabbit Polyclonal Phospho-STAT6-Y641 antibody

Catalogue No.

AP0456

Reactivity

Human

Immunogen

A phospho specific peptide corresponding to residues surrounding Y641 of human STAT6

Host

Rabbit

Applications

WB, IHC

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

110kDa

Formulation

Phospho-STAT6-Y641 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

Affinity purification

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

STAT6B antibody; STAT6C antibody; D12S1644 antibody; IL-4-STAT antibody;

Protein names

STAT6B; STAT6C; D12S1644; IL-4-STAT;

Protein function

Carries out a dual signal transduction and activation of transcription. Involved in IL4/interleukin-4- and IL3/interleukin-3-mediated signaling.

Protein sequence and domain

Belongs to the transcription factor STAT family.; Contains 1 SH2 domain.

Protein post-translational modifications

Tyrosine phosphorylated following stimulation by IL4/interleukin-4 and IL3/interleukin-3 (By similarity). Dephosphorylation on tyrosine residues by PTPN2 negatively regulates the IL4/interleukin-4 mediated signaling.

Protein cellular localization

Cytoplasm. Nucleus. Note=Translocated into the nucleus in response to phosphorylation.

Background

The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins. Alternative splicing results in multiple transcript variants.

Research area

<a href="http://antibodyplus.com/research-areas/">All research areas</a>><a href="http://antibodyplus.com/Transcription-Regulators/">Transcription Regulators</a>><a href="http://antibodyplus.com/product-tag/Stat/">Stat</a><br><a href="http://antibodyplus.com/product-tag/Transcription-Regulators/"&gt; (View all antibody categories related to Transcription Regulators)</a>

Note

AntibodyPlus can customize Phospho-STAT6-Y641 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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