Rabbit Polyclonal Phospho-SYN1-S9 antibody (AP0244)

$99.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IF
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit Polyclonal Phospho-SYN1-S9 antibody (AP0244)

Supplier: ABclonal Inc.

Recommended applications: WB,IF

Recommended dilution:

WB 1:500 – 1:2000
IF 1:100 – 1:200

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

Expand

SYNI antibody; SYN1a antibody; SYN1b antibody;
Brain protein 4.1 antibody|SYN 1 antibody|SYN 1a antibody|SYN 1b antibody|SYN I antibody|SYN1 antibody|SYN1_HUMAN antibody|SYN1a antibody|SYN1b antibody|Synapsin 1 antibody|Synapsin I antibody|Synapsin-1 antibody|Synapsin1 antibody|SynapsinI antibody|SYNI antibody|Anti-Synapsin I antibody – Synaptic Marker (ab64581)

SCBT cat No: sc-12913|sc-16852|sc-130606|sc-30037|sc-18205|sc-130219|sc-248320|sc-71794|sc-32275|sc-32276|

Name

Rabbit Polyclonal Phospho-SYN1-S9 antibody

Catalogue No.

AP0244

Reactivity

Human, Mouse, Rat

Immunogen

A phospho specific peptide corresponding to residues surrounding S9 of human SYN1

Host

Rabbit

Applications

WB, IF

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

77kDa

Formulation

Phospho-SYN1-S9 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

Affinity purification

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

SYNI antibody; SYN1a antibody; SYN1b antibody;

Protein names

SYNI; SYN1a; SYN1b;

Protein function

Neuronal phosphoprotein that coats synaptic vesicles, binds to the cytoskeleton, and is believed to function in the regulation of neurotransmitter release. The complex formed with NOS1 and CAPON proteins is necessary for specific nitric-oxid functions at a presynaptic level.

Protein sequence and domain

Belongs to the synapsin family. The A region binds phospholipids with a preference for negatively charged species.

Protein post-translational modifications

Substrate of at least four different protein kinases. It is probable that phosphorylation plays a role in the regulation of synapsin-1 in the nerve terminal.; Phosphorylation at Ser-9 dissociates synapsins from synaptic vesicles.

Protein cellular localization

Cell junction, synapse. Golgi apparatus .

Background

This gene is a member of the synapsin gene family. Synapsins encode neuronal phosphoproteins which associate with the cytoplasmic surface of synaptic vesicles. Family members are characterized by common protein domains, and they are implicated in synaptogenesis and the modulation of neurotransmitter release, suggesting a potential role in several neuropsychiatric diseases. This member of the synapsin family plays a role in regulation of axonogenesis and synaptogenesis. The protein encoded serves as a substrate for several different protein kinases and phosphorylation may function in the regulation of this protein in the nerve terminal. Mutations in this gene may be associated with X-linked disorders with primary neuronal degeneration such as Rett syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified.

Research area

<a href="http://antibodyplus.com/research-areas/">All research areas</a>><a href="http://antibodyplus.com/Transport-and-Trafficking/">Transport and Trafficking</a>><a href="http://antibodyplus.com/product-tag/Synapsin/">Synapsin</a><br><a href="http://antibodyplus.com/product-tag/Transport-and-Trafficking/"&gt; (View all antibody categories related to Transport and Trafficking)</a>

Note

AntibodyPlus can customize Phospho-SYN1-S9 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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