No products in the cart.
Rabbit Polyclonal Phospho-Synaptotagmin 1/2 (T202/199) antibody (STJ90747)
Supplier: St John’s Laboratory Ltd.
Recommended applications: WB, IHC, ELISA
Recommended dilution: WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:40000;
Recommended protocols: check protocols
Click or hover above images to see image description for Synaptotagmin 1/2 (phospho Thr202/199) Polyclonal Antibody.
Check alternative names for the antibodyExpand
SYT1 antibody, SVP65 antibody, SYT antibody,|DKFZp781D2042 antibody|FLJ42519 antibody|P65 antibody|SVP65 antibody|synaptotagmin 1 antibody|synaptotagmin 2 antibody|Synaptotagmin I antibody|Synaptotagmin II antibody|SYT antibody|SYT1 antibody|SYT2 antibody|SytI antibody|SytII antibody|Anti-Synaptotagmin 1 antibody (ab133856)
SCBT cat No: To be updated
Synaptotagmin 1/2 (phospho Thr202/199) Polyclonal Antibody
|Catalogue No.|| |
Human, Mouse, Rat
Phospho-Synaptotagmin 1/2 (T202/199) Polyclonal Antibody detects endogenous levels of Synaptotagmin 1/2 protein only when phosphorylated at T202/199.
Synthesized phospho-peptide derived from Synaptotagmin 1/2 (phospho Thr202/199) at AA range 150-230
WB, IHC, ELISA
|Recommended dilution|| |
WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:40000;
|Molecular weight|| |
Synaptotagmin 1/2 (phospho Thr202/199) Antibody was tube-contained. Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Synaptotagmin 1/2 (phospho Thr202/199) Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-20 Celsius degree. Avoid repeated freeze/thaw cycles.
|Alternative antibody names|| |
Synaptotagmin-1 antibody, Synaptotagmin I antibody, SytI antibody, p65 antibody
|Protein names|| |
Synaptotagmin-1 , Synaptotagmin I , SytI , p65
|Protein function|| |
May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone. A Ca2+-dependent interaction between synaptotagmin and putative receptors for activated protein kinase C has also been reported. It can bind to at least three additional proteins in a Ca2+-independent manner; these are neurexins, syntaxin and AP2. Plays a role in dendrite formation by melanocytes . / Ca2+
|Protein tissue specificity|| |
Expressed in melanocytes (PubMed:23999003).
|Involvement in disease|| |
Note: A SYT1 rare mutation has been found in a child with a severe neuro-developmental disorder. The individual harboring this variant shows early onset dyskinetic movement disorder, severe motor delay and profound cognitive impairment, suggesting that SYT1 may play a role in the pathogenesis of this neuro-developmental disorder. .
|Protein sequence and domain|| |
The first C2 domain mediates Ca2+-dependent phospholipid binding. / The second C2 domain mediates interaction with SV2A and probably with STN2. / Belongs to the synaptotagmin family. / Contains 2 C2 domains.
|Protein cellular localization|| |
Cytoplasmic vesicle > secretory vesicle membrane / Single-pass membrane protein / Cytoplasmic vesicle > secretory vesicle > synaptic vesicle membrane / Single-pass membrane protein / Cytoplasmic vesicle > secretory vesicle > chromaffin granule membrane / Single-pass membrane protein / Cytoplasm
AntibodyPlus can customize Synaptotagmin 1/2 (phospho Thr202/199) Antibody according to your requirement, including bulk product size,etc. Please contact email@example.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.
St John’s Laboratory Ltd.
|Product type|| |
There are no reviews for this product yet.
By submitting a review, get following benefits:
1. Receive $50 ABcoins as credit for each review.
2. First trial sample order will be fully refunded as credit.
3. Have a chance to win a $50 amazon gift card!
There is no extra validation for this product yet.
Check other extra validated antibodies below: