Rabbit Polyclonal Phospho-SYT2-T202 antibody (AP0460)

$99.00$259.00

Reactivity: Human,Mouse,Rat
Applications: IF
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit Polyclonal Phospho-SYT2-T202 antibody (AP0460)

Supplier: ABclonal Inc.

Recommended applications: IF

Recommended dilution:

IF 1:100 – 1:200

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

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SytII antibody;
Synaptotagmin 2 antibody|Synaptotagmin II antibody|Synaptotagmin-2 antibody|Synaptotagmin2 antibody|SynaptotagminII antibody|SYT 2 antibody|Syt II antibody|Syt2 antibody|SYT2_HUMAN antibody|SytII antibody|Anti-SYT2 antibody (ab113545)

SCBT cat No:

Name

Rabbit Polyclonal Phospho-SYT2-T202 antibody

Catalogue No.

AP0460

Reactivity

Human, Mouse, Rat

Immunogen

A phospho specific peptide corresponding to residues surrounding T202 of human SYT2

Host

Rabbit

Applications

IF

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

46kDa

Formulation

Phospho-SYT2-T202 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

Affinity purification

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

SytII antibody;

Protein names

SytII;

Protein function

Exhibits calcium-dependent phospholipid and inositol polyphosphate binding properties (By similarity). May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse (By similarity). Plays a role in dendrite formation by melanocytes (PubMed:23999003).

Protein tissue specificity

Expressed in melanocytes (PubMed:23999003).

Protein sequence and domain

Belongs to the synaptotagmin family.; Contains 2 C2 domains. The first C2 domain mediates Ca(2+)-dependent phospholipid binding.; The second C2 domain mediates interaction with Stonin 2. The second C2 domain mediates phospholipid and inositol polyphosphate binding in a calcium-independent manner.

Protein cellular localization

Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane ; Single-pass membrane protein . Cytoplasmic vesicle, secretory vesicle, chromaffin granule membrane ; Single-pass membrane protein . Note=Synaptic vesicles and chromaffin granules.

Background

Synaptotagmins, like SYT2, are integral membrane proteins of synaptic vesicles thought to serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis (Hilbush and Morgan, 1994

Research area

<a href="http://antibodyplus.com/research-areas/">All research areas</a>><a href="http://antibodyplus.com/Neurobiology/">Neurobiology</a>><a href="http://antibodyplus.com/product-tag/APBA2BP/">APBA2BP</a><br><a href="http://antibodyplus.com/product-tag/Neurobiology/"&gt; (View all antibody categories related to Neurobiology)</a>

Note

AntibodyPlus can customize Phospho-SYT2-T202 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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