Rabbit Polyclonal Phospho-TAL1 (S122) antibody (STJ90638)

$99.00$319.00

Reactivity: Human, Mouse
Applications: WB, IHC, ELISA
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

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Rabbit Polyclonal Phospho-TAL1 (S122) antibody (STJ90638)

Supplier: St John’s Laboratory Ltd.

Recommended applications: WB, IHC, ELISA

Recommended dilution: WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:10000;

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for TAL1 (phospho Ser122) Polyclonal Antibody.

Alternative names:

Check alternative names for the antibody

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TAL1 antibody, BHLHA17 antibody, SCL antibody, TCL5 antibody,|bHLHa17 antibody|Class A basic helix-loop-helix protein 17 antibody|OTTHUMP00000009563 antibody|OTTHUMP00000009564 antibody|SCL antibody|STEM CELL LEUKEMIA HEMATOPOIETIC TRANSCRIPTION FACTOR antibody|Stem cell protein antibody|T cell acute lymphocytic leukemia 1 antibody|T cell acute lymphocytic leukemia 1 protein antibody|T cell acute lymphocytic leukemia 1 protein antibody|T cell leukemia/lymphoma 5 protein antibody|T-cell acute lymphocytic leukemia protein 1 antibody|T-cell leukemia/lymphoma protein 5 antibody|Tal 1 antibody|Tal 1 product antibody|TAL 1 protein antibody|TAL-1 antibody|tal1 antibody|TAL1_HUMAN antibody|TCL 5 antibody|TCL5 antibody|Anti-Tal1 antibody (ab75738)
SCBT cat No: To be updated

 

Name

TAL1 (phospho Ser122) Polyclonal Antibody

Catalogue No.

STJ90638

Reactivity

Human, Mouse

Specificity

Phospho-TAL1 (S122) Polyclonal Antibody detects endogenous levels of TAL1 protein only when phosphorylated at S122.

Immunogen

Synthesized phospho-peptide derived from TAL1 (phospho Ser122) at AA range 70-150

Host

Rabbit

Applications

WB, IHC, ELISA

Recommended dilution

WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:10000;

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

45 kDa

Formulation

TAL1 (phospho Ser122) Antibody was tube-contained. Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration

1 mg/ml

Purification

TAL1 (phospho Ser122) Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Storage

-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

T-cell acute lymphocytic leukemia protein 1 antibody, TAL-1 antibody, Class A basic helix-loop-helix protein 17 antibody, bHLHa17 antibody, Stem cell protein antibody, T-cell leukemia/lymphoma protein 5 antibody

Database links

Human UniProt/Swiss-Prot:P17542;Mouse UniPort/Swiss-Prot: P22091;Rat UniProt/Swiss-Port: D3Z921;Human Entrez Gene: 6886;Mouse Entrez Gene: 21349;Rat Entrez Gene: Rn.9434

Protein names

T-cell acute lymphocytic leukemia protein 1 , TAL-1 , Class A basic helix-loop-helix protein 17 , bHLHa17 , Stem cell protein , T-cell leukemia/lymphoma protein 5

Protein function

Implicated in the genesis of hemopoietic malignancies. It may play an important role in hemopoietic differentiation. Serves as a positive regulator of erythroid differentiation (By similarity).

Protein tissue specificity

Leukemic stem cell.

Involvement in disease

Note: A chromosomal aberration involving TAL1 may be a cause of some T-cell acute lymphoblastic leukemias (T-ALL). Translocation t(1;14)(p32;q11) with T-cell receptor alpha chain (TCRA) genes. .

Protein sequence and domain

The helix-loop-helix domain is necessary and sufficient for the interaction with DRG1. / Contains 1 bHLH (basic helix-loop-helix) domain.

Protein post-translational modifications

Phosphorylated on serine residues. Phosphorylation of Ser-122 is strongly stimulated by hypoxia (By similarity). / Ubiquitinated; subsequent to hypoxia-dependent phosphorylation of Ser-122, ubiquitination targets the protein for rapid degradation via the ubiquitin system. This process may be characteristic for microvascular endothelial cells, since it could not be observed in large vessel endothelial cells (By similarity).

Protein cellular localization

Nucleus

Research area

All research areas>Transcription Regulators>TAL
(View all antibody categories related to Transcription Regulators)

Note

AntibodyPlus can customize TAL1 (phospho Ser122) Antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

St John’s Laboratory Ltd.

Product type

Primary antibody

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