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Rabbit Polyclonal Phospho-TAL1 (S122) antibody (STJ90638)
Supplier: St John’s Laboratory Ltd.
Recommended applications: WB, IHC, ELISA
Recommended dilution: WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:10000;
Recommended protocols: check protocols
Click or hover above images to see image description for TAL1 (phospho Ser122) Polyclonal Antibody.
Check alternative names for the antibodyExpand
TAL1 antibody, BHLHA17 antibody, SCL antibody, TCL5 antibody,|bHLHa17 antibody|Class A basic helix-loop-helix protein 17 antibody|OTTHUMP00000009563 antibody|OTTHUMP00000009564 antibody|SCL antibody|STEM CELL LEUKEMIA HEMATOPOIETIC TRANSCRIPTION FACTOR antibody|Stem cell protein antibody|T cell acute lymphocytic leukemia 1 antibody|T cell acute lymphocytic leukemia 1 protein antibody|T cell acute lymphocytic leukemia 1 protein antibody|T cell leukemia/lymphoma 5 protein antibody|T-cell acute lymphocytic leukemia protein 1 antibody|T-cell leukemia/lymphoma protein 5 antibody|Tal 1 antibody|Tal 1 product antibody|TAL 1 protein antibody|TAL-1 antibody|tal1 antibody|TAL1_HUMAN antibody|TCL 5 antibody|TCL5 antibody|Anti-Tal1 antibody (ab75738)
SCBT cat No: To be updated
TAL1 (phospho Ser122) Polyclonal Antibody
|Catalogue No.|| |
Phospho-TAL1 (S122) Polyclonal Antibody detects endogenous levels of TAL1 protein only when phosphorylated at S122.
Synthesized phospho-peptide derived from TAL1 (phospho Ser122) at AA range 70-150
WB, IHC, ELISA
|Recommended dilution|| |
WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:10000;
|Molecular weight|| |
TAL1 (phospho Ser122) Antibody was tube-contained. Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
TAL1 (phospho Ser122) Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-20 Celsius degree. Avoid repeated freeze/thaw cycles.
|Alternative antibody names|| |
T-cell acute lymphocytic leukemia protein 1 antibody, TAL-1 antibody, Class A basic helix-loop-helix protein 17 antibody, bHLHa17 antibody, Stem cell protein antibody, T-cell leukemia/lymphoma protein 5 antibody
|Protein names|| |
T-cell acute lymphocytic leukemia protein 1 , TAL-1 , Class A basic helix-loop-helix protein 17 , bHLHa17 , Stem cell protein , T-cell leukemia/lymphoma protein 5
|Protein function|| |
Implicated in the genesis of hemopoietic malignancies. It may play an important role in hemopoietic differentiation. Serves as a positive regulator of erythroid differentiation (By similarity).
|Protein tissue specificity|| |
Leukemic stem cell.
|Involvement in disease|| |
Note: A chromosomal aberration involving TAL1 may be a cause of some T-cell acute lymphoblastic leukemias (T-ALL). Translocation t(1;14)(p32;q11) with T-cell receptor alpha chain (TCRA) genes. .
|Protein sequence and domain|| |
The helix-loop-helix domain is necessary and sufficient for the interaction with DRG1. / Contains 1 bHLH (basic helix-loop-helix) domain.
|Protein post-translational modifications|| |
Phosphorylated on serine residues. Phosphorylation of Ser-122 is strongly stimulated by hypoxia (By similarity). / Ubiquitinated; subsequent to hypoxia-dependent phosphorylation of Ser-122, ubiquitination targets the protein for rapid degradation via the ubiquitin system. This process may be characteristic for microvascular endothelial cells, since it could not be observed in large vessel endothelial cells (By similarity).
|Protein cellular localization|| |
AntibodyPlus can customize TAL1 (phospho Ser122) Antibody according to your requirement, including bulk product size,etc. Please contact firstname.lastname@example.org. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.
St John’s Laboratory Ltd.
|Product type|| |
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