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Rabbit Polyclonal Phospho-TH (S71) antibody (STJ90749)
Supplier: St John’s Laboratory Ltd.
Recommended applications: WB, IHC, ELISA
Recommended dilution: WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:40000;
Recommended protocols: check protocols
Click or hover above images to see image description for TH (phospho Ser71) Polyclonal Antibody.
Check alternative names for the antibodyExpand
TH antibody, TYH antibody,|dystonia 14 antibody|DYT 5 antibody|DYT14 antibody|DYT5 antibody|DYT5a antibody|GCH 1 antibody|GCH antibody|Gch1 antibody|GCH1_HUMAN antibody|GTP CH 1 antibody|GTP CH I antibody|GTP cyclohydrolase 1 (dopa responsive dystonia) antibody|GTP cyclohydrolase 1 antibody|GTP cyclohydrolase I antibody|GTP-CH-I antibody|GTPCH 1 antibody|GTPCH1 antibody|Guanosine 5′ triphosphate cyclohydrolase I antibody|HPABH4B antibody|Anti-Tyrosine Hydroxylase antibody (ab112)
SCBT cat No: To be updated
TH (phospho Ser71) Polyclonal Antibody
|Catalogue No.|| |
Human, Mouse, Rat
Phospho-TH (S71) Polyclonal Antibody detects endogenous levels of TH protein only when phosphorylated at S71.
Synthesized phospho-peptide derived from TH (phospho Ser71) at AA range 10-90
WB, IHC, ELISA
|Recommended dilution|| |
WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:40000;
|Molecular weight|| |
TH (phospho Ser71) Antibody was tube-contained. Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
TH (phospho Ser71) Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-20 Celsius degree. Avoid repeated freeze/thaw cycles.
|Alternative antibody names|| |
Tyrosine 3-monooxygenase antibody, Tyrosine 3-hydroxylase antibody, TH antibody
|Protein names|| |
Tyrosine 3-monooxygenase , Tyrosine 3-hydroxylase , TH
|Protein function|| |
Plays an important role in the physiology of adrenergic neurons. / L-tyrosine + tetrahydrobiopterin + O2 = L-dopa + 4a-hydroxytetrahydrobiopterin. / Fe2+ / Phosphorylation leads to an increase in the catalytic activity. /
|Protein tissue specificity|| |
Mainly expressed in the brain and adrenal glands.
|Involvement in disease|| |
Segawa syndrome autosomal recessive (ARSEGS) [MIM:605407]: A form of DOPA-responsive dystonia presenting in infancy or early childhood. Dystonia is defined by the presence of sustained involuntary muscle contractions, often leading to abnormal postures. Some cases present with parkinsonian symptoms in infancy. Unlike all other forms of dystonia, it is an eminently treatable condition, due to a favorable response to L-DOPA. . Note: The disease is caused by mutations affecting the gene represented in this entry.; Note: May play a role in the pathogenesis of Parkinson disease (PD). A genome-wide copy number variation analysis has identified a 34 kilobase deletion over the TH gene in a PD patient but not in any controls. .
|Protein sequence and domain|| |
Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.
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St John’s Laboratory Ltd.
|Product type|| |
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