Rabbit Polyclonal Phospho-TH (S71) antibody (STJ90749)

$99.00$319.00

Reactivity: Human, Mouse, Rat
Applications: WB, IHC, ELISA
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

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Rabbit Polyclonal Phospho-TH (S71) antibody (STJ90749)

Supplier: St John’s Laboratory Ltd.

Recommended applications: WB, IHC, ELISA

Recommended dilution: WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:40000;

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for TH (phospho Ser71) Polyclonal Antibody.

Alternative names:

Check alternative names for the antibody

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TH antibody, TYH antibody,|dystonia 14 antibody|DYT 5 antibody|DYT14 antibody|DYT5 antibody|DYT5a antibody|GCH 1 antibody|GCH antibody|Gch1 antibody|GCH1_HUMAN antibody|GTP CH 1 antibody|GTP CH I antibody|GTP cyclohydrolase 1 (dopa responsive dystonia) antibody|GTP cyclohydrolase 1 antibody|GTP cyclohydrolase I antibody|GTP-CH-I antibody|GTPCH 1 antibody|GTPCH1 antibody|Guanosine 5′ triphosphate cyclohydrolase I antibody|HPABH4B antibody|Anti-Tyrosine Hydroxylase antibody (ab112)
SCBT cat No: To be updated

 

Name

TH (phospho Ser71) Polyclonal Antibody

Catalogue No.

STJ90749

Reactivity

Human, Mouse, Rat

Specificity

Phospho-TH (S71) Polyclonal Antibody detects endogenous levels of TH protein only when phosphorylated at S71.

Immunogen

Synthesized phospho-peptide derived from TH (phospho Ser71) at AA range 10-90

Host

Rabbit

Applications

WB, IHC, ELISA

Recommended dilution

WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:40000;

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

55 kDa

Formulation

TH (phospho Ser71) Antibody was tube-contained. Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration

1 mg/ml

Purification

TH (phospho Ser71) Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Storage

-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

Tyrosine 3-monooxygenase antibody, Tyrosine 3-hydroxylase antibody, TH antibody

Database links

Human UniProt/Swiss-Prot:P07101;Mouse UniPort/Swiss-Prot: P24529;Rat UniProt/Swiss-Port: P04177;Human Entrez Gene: 7054;Mouse Entrez Gene: 21823;Rat Entrez Gene: Rn.11082

Protein names

Tyrosine 3-monooxygenase , Tyrosine 3-hydroxylase , TH

Protein function

Plays an important role in the physiology of adrenergic neurons. / L-tyrosine + tetrahydrobiopterin + O2 = L-dopa + 4a-hydroxytetrahydrobiopterin. / Fe2+ / Phosphorylation leads to an increase in the catalytic activity. /

Protein tissue specificity

Mainly expressed in the brain and adrenal glands.

Involvement in disease

Segawa syndrome autosomal recessive (ARSEGS) [MIM:605407]: A form of DOPA-responsive dystonia presenting in infancy or early childhood. Dystonia is defined by the presence of sustained involuntary muscle contractions, often leading to abnormal postures. Some cases present with parkinsonian symptoms in infancy. Unlike all other forms of dystonia, it is an eminently treatable condition, due to a favorable response to L-DOPA. . Note: The disease is caused by mutations affecting the gene represented in this entry.; Note: May play a role in the pathogenesis of Parkinson disease (PD). A genome-wide copy number variation analysis has identified a 34 kilobase deletion over the TH gene in a PD patient but not in any controls. .

Protein sequence and domain

Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.

Research area

All research areas>Synthesis and Degradation>TH
(View all antibody categories related to Synthesis and Degradation)

Note

AntibodyPlus can customize TH (phospho Ser71) Antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

St John’s Laboratory Ltd.

Product type

Primary antibody

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