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Rabbit Polyclonal Phospho-TRbeta1 (S142) antibody (STJ90639)
Supplier: St John’s Laboratory Ltd.
Recommended applications: WB, ELISA
Recommended dilution: WB 1:500-1:2000; ELISA 1:5000;
Recommended protocols: check protocols
Click or hover above images to see image description for TRbeta1 (phospho Ser142) Polyclonal Antibody.
Check alternative names for the antibodyExpand
THRB antibody, ERBA2 antibody, NR1A2 antibody, THR1 antibody,|Avian erythroblastic leukemia viral (v erb a) oncogene homolog 2 antibody|C ERBA 2 antibody|C ERBA BETA antibody|c-erbA-2 antibody|c-erbA-beta antibody|ERBA 2 antibody|ERBA BETA antibody|ERBA2 antibody|Erythroblastic leukemia viral (v erb a) oncogene homolog 2 avian antibody|generalized resistance to thyroid hormone antibody|GRTH antibody|MGC126109 antibody|MGC126110 antibody|NR1A2 antibody|Nuclear receptor subfamily 1 group A member 2 antibody|Oncogene ERBA2 antibody|PRTH antibody|THB_HUMAN antibody|THR1 antibody|THRB 1 antibody|THRB 2 antibody|thrB antibody|THRB1 antibody|THRB2 antibody|Thyroid hormone nuclear receptor beta variant 1 antibody|Thyroid hormone receptor beta 1 antibody|Thyroid hormone receptor beta 2 antibody|Thyroid hormone receptor beta antibody|Thyroid hormone receptor, beta (erythroblastic leukemia viral (v erb a) oncogene homolog 2, avian) antibody|Anti-Thyroid Hormone Receptor beta antibody – ChIP Grade (ab5622)
SCBT cat No: To be updated
TRbeta1 (phospho Ser142) Polyclonal Antibody
|Catalogue No.|| |
Human, Mouse, Rat
Phospho-TRbeta1 (S142) Polyclonal Antibody detects endogenous levels of TRbeta1 protein only when phosphorylated at S142.
Synthesized phospho-peptide derived from TRbeta1 (phospho Ser142) at AA range 90-170
|Recommended dilution|| |
WB 1:500-1:2000; ELISA 1:5000;
|Molecular weight|| |
TRbeta1 (phospho Ser142) Antibody was tube-contained. Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
TRbeta1 (phospho Ser142) Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-20 Celsius degree. Avoid repeated freeze/thaw cycles.
|Alternative antibody names|| |
Thyroid hormone receptor beta antibody, Nuclear receptor subfamily 1 group A member 2 antibody, c-erbA-2 antibody, c-erbA-beta antibody
|Protein names|| |
Thyroid hormone receptor beta , Nuclear receptor subfamily 1 group A member 2 , c-erbA-2 , c-erbA-beta
|Protein function|| |
Nuclear hormone receptor that can act as a repressor or activator of transcription. High affinity receptor for thyroid hormones, including triiodothyronine and thyroxine.
|Involvement in disease|| |
Generalized thyroid hormone resistance (GTHR) [MIM:188570]: A disease characterized by goiter, abnormal mental functions, increased susceptibility to infections, abnormal growth and bone maturation, tachycardia and deafness. Affected individuals may also have attention deficit-hyperactivity disorders (ADHD) and language difficulties. GTHR patients also have high levels of circulating thyroid hormones (T3-T4), with normal or slightly elevated thyroid stimulating hormone (TSH). . Note: The disease is caused by mutations affecting the gene represented in this entry.; Generalized thyroid hormone resistance autosomal recessive (GTHRAR) [MIM:274300]: An autosomal recessive disorder characterized by goiter, clinical euthyroidism, end-organ unresponsiveness to thyroid hormone, abnormal growth and bone maturation, and deafness. Patients also have high levels of circulating thyroid hormones, with elevated thyroid stimulating hormone. . Note: The disease is caused by mutations affecting the gene represented in this entry.; Selective pituitary thyroid hormone resistance (PRTH) [MIM:145650]: Variant form of thyroid hormone resistance and is characterized by clinical hyperthyroidism, with elevated free thyroid hormones, but inappropriately normal serum TSH. Unlike GRTH, where the syndrome usually segregates with a dominant allele, the mode of inheritance in PRTH has not been established. . Note: The disease is caused by mutations affecting the gene represented in this entry.
|Protein sequence and domain|| |
Composed of three domains: a modulating N-terminal domain, a DNA-binding domain and a C-terminal ligand-binding domain. / Belongs to the nuclear hormone receptor family. NR1 subfamily. / Contains 1 nuclear receptor DNA-binding domain.
|Protein cellular localization|| |
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St John’s Laboratory Ltd.
|Product type|| |
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