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Rabbit Polyclonal Phospho-Unc18-1 (S313) antibody (STJ90471)
Supplier: St John’s Laboratory Ltd.
Recommended applications: WB, ELISA
Recommended dilution: WB 1:500-1:2000; ELISA 1:5000;
Recommended protocols: check protocols
Click or hover above images to see image description for Unc18-1 (phospho Ser313) Polyclonal Antibody.
Check alternative names for the antibodyExpand
STXBP1 antibody, UNC18A antibody,|FLJ37475 antibody|Munc 18 1 antibody|Munc 18a antibody|MUNC18 1 antibody|N-Sec1 antibody|Neuronal SEC1 antibody|NSec1 antibody|p67 antibody|Protein unc-18 homolog 1 antibody|Protein unc-18 homolog A antibody|Rb sec1 antibody|RBSEC1 antibody|STXB1_HUMAN antibody|STXBP1 antibody|Syntaxin binding protein 1 antibody|Syntaxin-binding protein 1 antibody|Unc 18 homolog antibody|Unc 18A antibody|Unc-18A antibody|Unc18 1 antibody|UNC18 antibody|Unc18-1 antibody|Anti-Munc18-1 antibody (ab3451)
SCBT cat No: To be updated
Unc18-1 (phospho Ser313) Polyclonal Antibody
|Catalogue No.|| |
Human, Mouse, Rat, Monkey
Phospho-Unc18-1 (S313) Polyclonal Antibody detects endogenous levels of Unc18-1 protein only when phosphorylated at S313.
Synthesized phospho-peptide derived from Unc18-1 (phospho Ser313) at AA range 250-330
|Recommended dilution|| |
WB 1:500-1:2000; ELISA 1:5000;
|Molecular weight|| |
Unc18-1 (phospho Ser313) Antibody was tube-contained. Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Unc18-1 (phospho Ser313) Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-20 Celsius degree. Avoid repeated freeze/thaw cycles.
|Alternative antibody names|| |
Syntaxin-binding protein 1 antibody, MUNC18-1 antibody, N-Sec1 antibody, Protein unc-18 homolog 1 antibody, Unc18-1 antibody, Protein unc-18 homolog A antibody, Unc-18A antibody, p67 antibody
|Protein names|| |
Syntaxin-binding protein 1 , MUNC18-1 , N-Sec1 , Protein unc-18 homolog 1 , Unc18-1 , Protein unc-18 homolog A , Unc-18A , p67
|Protein function|| |
May participate in the regulation of synaptic vesicle docking and fusion, possibly through interaction with GTP-binding proteins. Essential for neurotransmission and binds syntaxin, a component of the synaptic vesicle fusion machinery probably in a 1:1 ratio. Can interact with syntaxins 1, 2, and 3 but not syntaxin 4. May play a role in determining the specificity of intracellular fusion reactions.
|Protein tissue specificity|| |
Brain and spinal cord. Highly enriched in axons.
|Involvement in disease|| |
Epileptic encephalopathy, early infantile, 4 (EIEE4) [MIM:612164]: A severe form of epilepsy characterized by frequent tonic seizures or spasms beginning in infancy with a specific EEG finding of suppression-burst patterns, characterized by high-voltage bursts alternating with almost flat suppression phases. Affected individuals have neonatal or infantile onset of seizures, profound mental retardation, and MRI evidence of brain hypomyelination. . Note: The disease is caused by mutations affecting the gene represented in this entry.
|Protein sequence and domain|| |
Belongs to the STXBP/unc-18/SEC1 family.
|Protein cellular localization|| |
Cytoplasm > cytosol / Membrane; Peripheral membrane protein
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St John’s Laboratory Ltd.
|Product type|| |
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