Rabbit Polyclonal Phospho-Unc18-1 (S313) antibody (STJ90471)

$99.00$319.00

Reactivity: Human, Mouse, Rat, Monkey
Applications: WB, ELISA
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

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Rabbit Polyclonal Phospho-Unc18-1 (S313) antibody (STJ90471)

Supplier: St John’s Laboratory Ltd.

Recommended applications: WB, ELISA

Recommended dilution: WB 1:500-1:2000; ELISA 1:5000;

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Unc18-1 (phospho Ser313) Polyclonal Antibody.

Alternative names:

Check alternative names for the antibody

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STXBP1 antibody, UNC18A antibody,|FLJ37475 antibody|Munc 18 1 antibody|Munc 18a antibody|MUNC18 1 antibody|N-Sec1 antibody|Neuronal SEC1 antibody|NSec1 antibody|p67 antibody|Protein unc-18 homolog 1 antibody|Protein unc-18 homolog A antibody|Rb sec1 antibody|RBSEC1 antibody|STXB1_HUMAN antibody|STXBP1 antibody|Syntaxin binding protein 1 antibody|Syntaxin-binding protein 1 antibody|Unc 18 homolog antibody|Unc 18A antibody|Unc-18A antibody|Unc18 1 antibody|UNC18 antibody|Unc18-1 antibody|Anti-Munc18-1 antibody (ab3451)
SCBT cat No: To be updated

 

Name

Unc18-1 (phospho Ser313) Polyclonal Antibody

Catalogue No.

STJ90471

Reactivity

Human, Mouse, Rat, Monkey

Specificity

Phospho-Unc18-1 (S313) Polyclonal Antibody detects endogenous levels of Unc18-1 protein only when phosphorylated at S313.

Immunogen

Synthesized phospho-peptide derived from Unc18-1 (phospho Ser313) at AA range 250-330

Host

Rabbit

Applications

WB, ELISA

Recommended dilution

WB 1:500-1:2000; ELISA 1:5000;

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

65 kDa

Formulation

Unc18-1 (phospho Ser313) Antibody was tube-contained. Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration

1 mg/ml

Purification

Unc18-1 (phospho Ser313) Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Storage

-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

Syntaxin-binding protein 1 antibody, MUNC18-1 antibody, N-Sec1 antibody, Protein unc-18 homolog 1 antibody, Unc18-1 antibody, Protein unc-18 homolog A antibody, Unc-18A antibody, p67 antibody

Database links

Human UniProt/Swiss-Prot:P61764;Mouse UniPort/Swiss-Prot: O08599;Rat UniProt/Swiss-Port: P61765;Human Entrez Gene: 6812;Mouse Entrez Gene: 20910;Rat Entrez Gene: Rn.80843

Protein names

Syntaxin-binding protein 1 , MUNC18-1 , N-Sec1 , Protein unc-18 homolog 1 , Unc18-1 , Protein unc-18 homolog A , Unc-18A , p67

Protein function

May participate in the regulation of synaptic vesicle docking and fusion, possibly through interaction with GTP-binding proteins. Essential for neurotransmission and binds syntaxin, a component of the synaptic vesicle fusion machinery probably in a 1:1 ratio. Can interact with syntaxins 1, 2, and 3 but not syntaxin 4. May play a role in determining the specificity of intracellular fusion reactions.

Protein tissue specificity

Brain and spinal cord. Highly enriched in axons.

Involvement in disease

Epileptic encephalopathy, early infantile, 4 (EIEE4) [MIM:612164]: A severe form of epilepsy characterized by frequent tonic seizures or spasms beginning in infancy with a specific EEG finding of suppression-burst patterns, characterized by high-voltage bursts alternating with almost flat suppression phases. Affected individuals have neonatal or infantile onset of seizures, profound mental retardation, and MRI evidence of brain hypomyelination. . Note: The disease is caused by mutations affecting the gene represented in this entry.

Protein sequence and domain

Belongs to the STXBP/unc-18/SEC1 family.

Protein cellular localization

Cytoplasm > cytosol / Membrane; Peripheral membrane protein

Research area

All research areas>Neurobiology>Unc18
(View all antibody categories related to Neurobiology)

Note

AntibodyPlus can customize Unc18-1 (phospho Ser313) Antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

St John’s Laboratory Ltd.

Product type

Primary antibody

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