Rabbit Polyclonal Phospho-YB-1 (S102) antibody (STJ90649)

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Reactivity: Human, Mouse, Rat
Applications: WB, ELISA
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

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Rabbit Polyclonal Phospho-YB-1 (S102) antibody (STJ90649)

Supplier: St John’s Laboratory Ltd.

Recommended applications: WB, ELISA

Recommended dilution: WB 1:500-1:2000; ELISA 1:40000;

Recommended protocols: check protocols

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Click or hover above images to see image description for YB-1 (phospho Ser102) Polyclonal Antibody.

Alternative names:

Check alternative names for the antibody

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YBX1 antibody, NSEP1 antibody, YB1 antibody,|BP 8 antibody|CBF-A antibody|CCAAT binding transcription factor I subunit A antibody|CCAAT-binding transcription factor I subunit A antibody|CSDA2 antibody|CSDB antibody|DBPB antibody|DNA binding protein B antibody|DNA-binding protein B antibody|EFI-A antibody|Enhancer factor I subunit A antibody|MDR NF1 antibody|MGC104858 antibody|MGC110976 antibody|MGC117250 antibody|NSEP 1 antibody|NSEP1 antibody|Nuclease sensitive element binding protein 1 antibody|Nuclease-sensitive element-binding protein 1 antibody|p50 antibody|Q15905 antibody|Y-box binding protein 1 antibody|Y-box transcription factor antibody|Y-box-binding protein 1 antibody|YB 1 antibody|YB-1 antibody|YBOX1_HUMAN antibody|YBX 1 antibody|ybx1 antibody|Anti-YB1 antibody (ab12148)
SCBT cat No: To be updated

 

Name

YB-1 (phospho Ser102) Polyclonal Antibody

Catalogue No.

STJ90649

Reactivity

Human, Mouse, Rat

Specificity

Phospho-YB-1 (S102) Polyclonal Antibody detects endogenous levels of YB-1 protein only when phosphorylated at S102.

Immunogen

Synthesized phospho-peptide derived from YB-1 (phospho Ser102) at AA range 40-120

Host

Rabbit

Applications

WB, ELISA

Recommended dilution

WB 1:500-1:2000; ELISA 1:40000;

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

36 kDa

Formulation

YB-1 (phospho Ser102) Antibody was tube-contained. Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration

1 mg/ml

Purification

YB-1 (phospho Ser102) Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Storage

-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

Nuclease-sensitive element-binding protein 1 antibody, CCAAT-binding transcription factor I subunit A antibody, CBF-A antibody, DNA-binding protein B antibody, DBPB antibody, Enhancer factor I subunit A antibody, EFI-A antibody, Y-box transcription factor antibody, Y-box-binding protein 1 antibody, YB-1 antibody

Database links

Human UniProt/Swiss-Prot:P67809;Mouse UniPort/Swiss-Prot: P62960;Rat UniProt/Swiss-Port: P62961;Human Entrez Gene: 4904;Mouse Entrez Gene: 22608;Rat Entrez Gene: Rn.110976

Protein names

Nuclease-sensitive element-binding protein 1 , CCAAT-binding transcription factor I subunit A , CBF-A , DNA-binding protein B , DBPB , Enhancer factor I subunit A , EFI-A , Y-box transcription factor , Y-box-binding protein 1 , YB-1

Protein function

Mediates pre-mRNA alternative splicing regulation. Binds to splice sites in pre-mRNA and regulates splice site selection. Binds and stabilizes cytoplasmic mRNA. Contributes to the regulation of translation by modulating the interaction between the mRNA and eukaryotic initiation factors (By similarity). Regulates the transcription of numerous genes. Its transcriptional activity on the multidrug resistance gene MDR1 is enhanced in presence of the APEX1 acetylated form at ‘Lys-6’ and ‘Lys-7’. Binds to promoters that contain a Y-box (5′-CTGATTGGCCAA-3′), such as MDR1 and HLA class II genes. Promotes separation of DNA strands that contain mismatches or are modified by cisplatin. Has endonucleolytic activity and can introduce nicks or breaks into double-stranded DNA (in vitro). May play a role in DNA repair. Component of the CRD-mediated complex that promotes MYC mRNA stability. Binds preferentially to the 5′-[CU]CUGCG-3′ motif in vitro. / The secreted form acts as an extracellular mitogen and stimulates cell migration and proliferation.

Protein sequence and domain

Contains 1 CSD (cold-shock) domain.

Protein post-translational modifications

Ubiquitinated by RBBP6; leading to a decrease of YBX1 transcactivational ability. / In the absence of phosphorylation the protein is retained in the cytoplasm. / Cleaved by a 20S proteasomal protease in response to agents that damage DNA. Cleavage takes place in the absence of ubiquitination and ATP. The resulting N-terminal fragment accumulates in the nucleus (By similarity).

Protein cellular localization

Cytoplasm / Nucleus / Cytoplasmic granule / Secreted

Research area

All research areas>Transcription Regulators>YB-1
(View all antibody categories related to Transcription Regulators)

Note

AntibodyPlus can customize YB-1 (phospho Ser102) Antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

St John’s Laboratory Ltd.

Product type

Primary antibody

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