Rabbit Polyclonal Phospho-YWHAZ-S58 antibody (AP0195)

$99.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC,IF
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit Polyclonal Phospho-YWHAZ-S58 antibody (AP0195)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC,IF

Recommended dilution:

WB 1:500 – 1:2000
IHC 1:50 – 1:100
IF 1:100 – 1:200

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit Polyclonal Phospho-YWHAZ-S58 antibody.

Alternative names:

Check alternative names for the antibody

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YWHAD antibody; KCIP-1 antibody; 14-3-3-zeta antibody;
14 3 3 delta antibody|14 3 3 protein zeta/delta antibody|14 3 3 protein/cytosolic phospholipase A2 antibody|14 3 3 zeta antibody|14-3-3 protein zeta/delta antibody|1433Z_HUMAN antibody|Epididymis luminal protein 4 antibody|Epididymis secretory protein Li 3 antibody|HEL S 3 antibody|HEL4 antibody|KCIP-1 antibody|KCIP1 antibody|MGC111427 antibody|MGC126532 antibody|MGC138156 antibody|Phospholipase A2 antibody|Protein kinase C inhibitor protein 1 antibody|Tyrosine 3 monooxygenase/tryptophan 5 monooxygenase activation protein, delta polypeptide antibody|Tyrosine 3 monooxygenase/tryptophan 5 monooxygenase activation protein, zeta antibody|Tyrosine 3 monooxygenase/tryptophan 5 monooxygenase activation protein, zeta polypeptide antibody|Tyrosine 3/tryptophan 5 monooxygenase activation protein, zeta polypeptide antibody|YWHAD antibody|YWHAZ antibody|Anti-14-3-3 zeta antibody (ab51129)

SCBT cat No: sc-293415|sc-1019|sc-31964|sc-31965|

Name

Rabbit Polyclonal Phospho-YWHAZ-S58 antibody

Catalogue No.

AP0195

Reactivity

Human, Mouse, Rat

Immunogen

A phospho specific peptide corresponding to residues surrounding S58 of human YWHAZ

Host

Rabbit

Applications

WB, IHC, IF

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

28kDa

Formulation

Phospho-YWHAZ-S58 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

Affinity purification

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

YWHAD antibody; KCIP-1 antibody; 14-3-3-zeta antibody;

Protein names

YWHAD; KCIP-1; 14-3-3-zeta;

Protein function

Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner.

Protein sequence and domain

Belongs to the 14-3-3 family.

Protein post-translational modifications

The delta, brain-specific form differs from the zeta form in being phosphorylated (By similarity). Phosphorylation on Ser-184 by MAPK8; promotes dissociation of BAX and translocation of BAX to mitochondria. Phosphorylation on Thr-232; inhibits binding of RAF1. Phosphorylated on Ser-58 by PKA and protein kinase C delta type catalytic subunit in a sphingosine-dependent fashion. Phosphorylation on Ser-58 by PKA; disrupts homodimerization and heterodimerization with YHAE and TP53.

Protein cellular localization

Cytoplasm . Melanosome . Note=Located to stage I to stage IV melanosomes.

Background

This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and sheep orthologs. The encoded protein interacts with IRS1 protein, suggesting a role in regulating insulin sensitivity. Several transcript variants that differ in the 5' UTR but that encode the same protein have been identified for this gene.

Note

AntibodyPlus can customize Phospho-YWHAZ-S58 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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