Rabbit polyclonal PITRM1 antibody (A8362)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal PITRM1 antibody (A8362)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:100

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit polyclonal PITRM1 antibody.

Alternative names:

Check alternative names for the antibody

Expand

MP1 antibody, PreP antibody
hMP1 antibody|hPreP antibody|KIAA1104 antibody|Metalloprotease 1 antibody|MGC138192 antibody|MGC141929 antibody|mitochondrial antibody|MP1 antibody|Pitrilysin metallopeptidase 1 antibody|Pitrilysin metalloproteinase 1 antibody|PITRM 1 antibody|PITRM1 antibody|PreP antibody|PreP peptidasome antibody|PREP_HUMAN antibody|Presequence protease antibody|Presequence protease mitochondrial antibody|Anti-PITRM1 antibody (ab111681)

SCBT cat No: sc-82316|

Name

Rabbit polyclonal PITRM1 antibody

Catalogue No.

A8362

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human PITRM1

Host

Rabbit

Applications

WB, IHC

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:100

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 117kDa/Observed: Refer to figures

Formulation

PITRM1 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

PITRM1 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

MP1 antibody, PreP antibody

Database links

Human UniProt/Swiss-Prot:Q5JRX3

Protein names

MP1, PreP

Protein function

ATP-independent protease that degrades mitochondrial transit peptides after their cleavage. Also degrades other unstructured peptides. Specific for peptides in the range of 10 to 65 residues. Able to degrade amyloid beta A4 (APP) protein when it accumulates in mitochondrion, suggesting a link with Alzheimer disease. Shows a preference for cleavage after small polar residues and before basic residues, but without any positional preference.

Protein tissue specificity

Widely expressed. Expressed at higher level in muscle and heart compared to brain, pancreas, liver, lung and placenta.

Protein sequence and domain

Belongs to the peptidase M16 family. PreP subfamily.

Protein post-translational modifications

The disulfide bond may lock the enzyme in a closed conformation under oxidized conditions, suggesting that it may participate in redox regulation of the enzyme.

Protein cellular localization

Mitochondrion matrix .

Note

AntibodyPlus can customize PITRM1 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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