Rabbit Polyclonal PLB1 antibody (A10429)

$99.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit Polyclonal PLB1 antibody (A10429)

Supplier: ABclonal Inc.

Recommended applications: WB

Recommended dilution:

WB 1:500 – 1:2000

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

Expand

PLB antibody; PLB/LIP antibody;
hPLB antibody|Lysophospholipase antibody|Phospholipase A2 antibody|Phospholipase B antibody|Phospholipase B/lipase antibody|Phospholipase B1 antibody|Phospholipase B1 membrane associated antibody|PLB 1 antibody|PLB antibody|PLB/LIP antibody|Anti-PLB1 antibody (ab92915)

SCBT cat No:

Name

Rabbit Polyclonal PLB1 antibody

Catalogue No.

A10429

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human PLB1

Host

Rabbit

Applications

WB

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

160kDa

Formulation

PLB1 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

Affinity purification

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

PLB antibody; PLB/LIP antibody;

Protein names

PLB; PLB/LIP;

Protein function

Membrane-associated phospholipase. Exhibits a calcium-independent broad substrate specificity including phospholipase A2/lysophospholipase activity. Preferential hydrolysis at the sn-2 position of diacylphospholipids and diacyglycerol, whereas it shows no positional specificity toward triacylglycerol. Exhibits also esterase activity toward p-nitrophenyl. May act on the brush border membrane to facilitate the absorption of digested lipids (By similarity).

Protein tissue specificity

Expressed in the epidermis (at protein level).

Protein sequence and domain

Belongs to the 'GDSL' lipolytic enzyme family. Phospholipase B1 subfamily. Repeat 2 contains the catalytic domain.

Protein post-translational modifications

Undergoes proteolytic cleavage in the ileum.

Protein cellular localization

Apical cell membrane ; Single-pass type I membrane protein . Note=Present in the intestinal brush border membranes.

Background

This gene encodes a membrane-associated phospholipase that displays lysophospholipase and phospholipase A2 activities through removal of sn-1 and sn-2 fatty acids of glycerophospholipids. In addition, it displays lipase and retinyl ester hydrolase activities. The encoded protein is highly conserved and is composed of a large, glycosylated extracellular domain composed of four tandem homologous domains, followed by a hydrophobic segment that anchors the enzyme to the membrane and a short C-terminal cytoplasmic tail. This gene has been identified as a candidate rheumatoid arthritis risk gene.

Research area

<a href="http://antibodyplus.com/research-areas/">All research areas</a>><a href="http://antibodyplus.com/Synthesis-and-Degradation/">Synthesis and Degradation</a>><a href="http://antibodyplus.com/product-tag/cPLA/">cPLA</a><br><a href="http://antibodyplus.com/product-tag/Synthesis-and-Degradation/"&gt; (View all antibody categories related to Synthesis and Degradation)</a>

Note

AntibodyPlus can customize PLB1 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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