Rabbit polyclonal PLEKHF2 antibody (A7603)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal PLEKHF2 antibody (A7603)

Supplier: ABclonal Inc.

Recommended applications: WB

Recommended dilution:

WB 1:500 – 1:2000

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit polyclonal PLEKHF2 antibody.

Alternative names:

Check alternative names for the antibody

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EAPF antibody, PHAFIN2 antibody, ZFYVE18 antibody
110070J07Rik antibody|AA673237 antibody|FLJ13187 antibody|PH and FYVE domain containing protein 2 antibody|PH and FYVE domain-containing protein 2 antibody|PH domain containing family F member 2 antibody|PH domain-containing family F member 2 antibody|Phafin 2 antibody|Phafin-2 antibody|PHAFIN2 antibody|PKHF2_HUMAN antibody|pleckstrin homology domain containing, family F (with FYVE domain) member 2 antibody|pleckstrin homology domain containing, family F (with FYVE domain) member2 antibody|Pleckstrin homology domain-containing family F member 2 antibody|Plekhf2 antibody|ZFYVE18 antibody|Zinc finger FYVE domain containing protein 18 antibody|Zinc finger FYVE domain-containing protein 18 antibody|Anti-PLEKHF2 antibody (ab127047)

SCBT cat No: sc-87358|

Name

Rabbit polyclonal PLEKHF2 antibody

Catalogue No.

A7603

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human PLEKHF2

Host

Rabbit

Applications

WB

Recommended dilution

WB 1:500 – 1:2000

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 28kDa/Observed: Refer to figures

Formulation

PLEKHF2 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

PLEKHF2 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

EAPF antibody, PHAFIN2 antibody, ZFYVE18 antibody

Database links

Human UniProt/Swiss-Prot:Q9H8W4

Protein names

EAPF, PHAFIN2, ZFYVE18

Protein function

May play a role in early endosome fusion upstream of RAB5, hence regulating receptor trafficking and fluid-phase transport. Enhances cellular sensitivity to TNF-induced apoptosis .

Protein tissue specificity

Expressed in placenta, ovary and small intestine, as well as in heart and pancreas. Also expressed in peripheral blood mononuclear cells and dendritic cells.

Protein sequence and domain

The PH and FYVE domains may be important for TNF-induced localization to the endoplasmic reticulum and for enhanced cellular sensitivity to TNF-induced apoptosis . The FYVE domain is important for binding to the endosomal membrane.Contains 1 FYVE-type zinc finger.; Contains 1 PH domain.

Protein cellular localization

Early endosome membrane ; Peripheral membrane protein . Endoplasmic reticulum . Note: Colocalizes with EEA1 and RAB5 at endosomal membrane fusion hot spots . May translocate to the endoplasmic reticulum in the early phase of apoptosis .

Note

AntibodyPlus can customize PLEKHF2 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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