Rabbit polyclonal PMAIP1 antibody (A9801)

$69.00$259.00

Reactivity: Human
Applications: WB
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal PMAIP1 antibody (A9801)

Supplier: ABclonal Inc.

Recommended applications: WB

Recommended dilution:

WB 1:500 – 1:2000

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

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Adult T cell leukemia derived PMA responsive antibody|APR antibody|APR_HUMAN antibody|ATL-derived antibody|Immediate early response protein APR antibody|Immediate-early-response protein APR antibody|NOXA antibody|Phorbol 12 myristate 13 acetate induced protein 1 antibody|Phorbol-12-myristate-13-acetate-induced protein 1 antibody|PMA induced protein 1 antibody|PMA-induced protein 1 antibody|PMA-responsive gene antibody|Pmaip1 antibody|Protein Noxa antibody|Anti-Noxa antibody [114C307] (ab13654)

SCBT cat No: sc-22764|sc-30209|

Name

Rabbit polyclonal PMAIP1 antibody

Catalogue No.

A9801

Reactivity

Human

Immunogen

A synthetic peptide of human PMAIP1

Host

Rabbit

Applications

WB

Recommended dilution

WB 1:500 – 1:2000

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 6kDa/Observed: Refer to figures

Formulation

PMAIP1 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

PMAIP1 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Database links

Human UniProt/Swiss-Prot:Q13794

Protein function

Promotes activation of caspases and apoptosis. Promotes mitochondrial membrane changes and efflux of apoptogenic proteins from the mitochondria. Contributes to p53/TP53-dependent apoptosis after radiation exposure. Promotes proteasomal degradation of MCL1. Competes with BAK1 for binding to MCL1 and can displace BAK1 from its binding site on MCL1 (By similarity). Competes with BIM/BCL2L11 for binding to MCL1 and can displace BIM/BCL2L11 from its binding site on MCL1.

Protein tissue specificity

Highly expressed in adult T-cell leukemia cell line.

Protein sequence and domain

The BH3 motif is essential for pro-apoptotic activity.Belongs to the PMAIP1 family.

Protein cellular localization

Mitochondrion .

Note

AntibodyPlus can customize PMAIP1 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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