Rabbit polyclonal PNP antibody (A5778)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal PNP antibody (A5778)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

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NP antibody, PUNP antibody, PRO1837 antibody
FLJ94043 antibody|FLJ97288 antibody|FLJ97312 antibody|Inosine phosphorylase antibody|Inosine-guanosine phosphorylase antibody|MGC117396 antibody|MGC125915 antibody|MGC125916 antibody|NP antibody|Np1 antibody|Nucleoside phosphorylase antibody|PNP antibody|Pnp1 antibody|PNPH_HUMAN antibody|PRO1837 antibody|PUNP antibody|Purine nucleoside orthophosphate ribosyltransferase antibody|Purine nucleoside phosphorylase 5a antibody|Purine nucleoside phosphorylase antibody|Anti-Nucleoside phosphorylase antibody [EPR5715] (ab109447)

SCBT cat No: sc-47333|sc-271890|sc-365132|sc-47334|sc-365551|sc-365081|

Name

Rabbit polyclonal PNP antibody

Catalogue No.

A5778

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human PNP

Host

Rabbit

Applications

WB, IHC

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 32kDa/Observed: Refer to Figures

Formulation

PNP antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

PNP antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

NP antibody, PUNP antibody, PRO1837 antibody

Database links

Human UniProt/Swiss-Prot:P00491

Protein names

NP, PUNP, PRO1837

Protein function

The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

Protein tissue specificity

Expressed in red blood cells; overexpressed in red blood cells (cytoplasm) of patients with hereditary non-spherocytic hemolytic anemia of unknown etiology.

Protein sequence and domain

Belongs to the PNP/MTAP phosphorylase family.

Protein cellular localization

Cytoplasm, cytoskeleton . Cytoplasm .

Background

This gene encodes an enzyme which reversibly catalyzes the phosphorolysis of purine nucleosides. The enzyme is trimeric, containing three identical subunits. Mutations which result in nucleoside phosphorylase deficiency result in defective T-cell (cell-mediated) immunity but can also affect B-cell immunity and antibody responses. Neurologic disorders may also be apparent in patients with immune defects. A known polymorphism at aa position 51 that does not affect enzyme activity has been described. A pseudogene has been identified on chromosome 2.

Note

AntibodyPlus can customize PNP antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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