Rabbit polyclonal PNPLA2 antibody (A6245)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal PNPLA2 antibody (A6245)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

Expand

ATGL antibody, TTS2 antibody, PEDF-R antibody, FP17548 antibody, TTS-2.2 antibody, iPLA2zeta antibody, 1110001C14Rik antibody
1110001C14Rik antibody|Adipose triglyceride lipase antibody|ATGL antibody|ATGL DESNUTRIN antibody|Calcium independent phospholipase A2 antibody|Calcium-independent phospholipase A2 antibody|Desnutrin antibody|EC 3.1.1.3 antibody|FP17548 antibody|IPLA2 zeta antibody|IPLA2-zeta antibody|PATATIN LIKE PHOSPHOLIPASE DOMAIN CONTAINING PROTEIN 2 antibody|Patatin-like phospholipase domain-containing protein 2 antibody|PEDF R antibody|PHOSPHOLIPASE A2 CALCIUM INDEPENDENT ZETA antibody|Pigment epithelium derived factor antibody|Pigment epithelium-derived factor antibody|plpl antibody|plpl2 antibody|PLPL2_HUMAN antibody|Pnpla2 antibody|Transport secretion protein 2 antibody|Transport secretion protein 2.2 antibody|Transport-secretion protein 2 antibody|Triglyceride hydrolase antibody|TTS 2.2 antibody|TTS2 antibody|TTS2.2 antibody|ZETA antibody|Anti-Adipose Triglyceride Lipase antibody [EPR3444(2)] (ab109251)

SCBT cat No: sc-365278|sc-67355|sc-50222|sc-50223|

Name

Rabbit polyclonal PNPLA2 antibody

Catalogue No.

A6245

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human PNPLA2

Host

Rabbit

Applications

WB, IHC

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 55kDa/Observed: Refer to Figures

Formulation

PNPLA2 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

PNPLA2 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

ATGL antibody, TTS2 antibody, PEDF-R antibody, FP17548 antibody, TTS-2.2 antibody, iPLA2zeta antibody, 1110001C14Rik antibody

Database links

Human UniProt/Swiss-Prot:Q96AD5

Protein names

ATGL, TTS2, PEDF-R, FP17548, TTS-2.2, iPLA2zeta, 1110001C14Rik

Protein function

Catalyzes the initial step in triglyceride hydrolysis in adipocyte and non-adipocyte lipid droplets . Also has acylglycerol transacylase activity. May act coordinately with LIPE/HLS within the lipolytic cascade. Regulates adiposome size and may be involved in the degradation of adiposomes . May play an important role in energy homeostasis. May play a role in the response of the organism to starvation, enhancing hydrolysis of triglycerides and providing free fatty acids to other tissues to be oxidized in situations of energy depletion.

Protein tissue specificity

Highest expression in adipose tissue. Also detected in heart, skeletal muscle, and portions of the gastrointestinal tract. Detected in normal retina and retinoblastoma cells. Detected in retinal pigment epithelium and, at lower intensity, in the inner segments of photoreceptors and in the ganglion cell layer of the neural retina (at protein level).

Protein sequence and domain

Contains 1 patatin domain.

Protein post-translational modifications

Phosphorylation at Ser-404 by PKA is increased during fasting and moderate intensity exercise, and moderately increases lipolytic activity (By similarity). Phosphorylation at Ser-404 is increased upon beta-adrenergic stimulation.

Protein cellular localization

Lipid droplet. Cell membrane; Single-pass type II membrane protein.

Background

This gene encodes an enzyme which catalyzes the first step in the hydrolysis of triglycerides in adipose tissue. Mutations in this gene are associated with neutral lipid storage disease with myopathy.

Note

AntibodyPlus can customize PNPLA2 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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