Rabbit polyclonal POLD1 antibody (A5323)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC,IF
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal POLD1 antibody (A5323)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC,IF

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200 IF 1:50 – 1:200

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

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CDC2 antibody, MDPL antibody, POLD antibody, CRCS10 antibody
Polymerase (DNA directed) delta 1 catalytic subunit antibody|CDC2 antibody|CDC2 homolog antibody|CRCS10 antibody|DNA directed DNA polymerase delta 1 antibody|DNA directed polymerase delta 1 antibody|DNA pol delta 1 antibody|DNA polymerase delta catalytic subunit antibody|DNA polymerase subunit delta p125 antibody|DPOD1_HUMAN antibody|MDPL antibody|POLD antibody|POLD 1 antibody|POLD1 antibody|Polymerase (DNA directed) delta 1 catalytic subunit 125kDa antibody|Polymerase (DNA) delta 1 catalytic subunit antibody|Polymerase DNA directed delta 1 catalytic subunit 125kD antibody|polymerase, DNA, delta antibody|Anti-DNA Polymerase delta, catalytic subunit antibody [EPR15118] (ab186407)

SCBT cat No: sc-373731|

Name

Rabbit polyclonal POLD1 antibody

Catalogue No.

A5323

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human POLD1

Host

Rabbit

Applications

WB, IHC, IF

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200
IF 1:50 – 1:200

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 123kDa/Observed: Refer to Figures

Formulation

POLD1 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

POLD1 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

CDC2 antibody, MDPL antibody, POLD antibody, CRCS10 antibody

Database links

Human UniProt/Swiss-Prot:P28340

Protein names

CDC2, MDPL, POLD, CRCS10

Protein function

Possesses two enzymatic activities: DNA synthesis (polymerase) and an exonucleolytic activity that degrades single stranded DNA in the 3′- to 5′-direction. Required with its accessory proteins (proliferating cell nuclear antigen (PCNA) and replication factor C (RFC) or activator 1) for leading strand synthesis. Also involved in completing Okazaki fragments initiated by the DNA polymerase alpha/primase complex.

Protein tissue specificity

Expressed across a panel of tissues, with high levels of expression in heart and lung.

Protein sequence and domain

The CysB motif binds 1 4Fe-4S cluster and is required for the formation of polymerase complexes.Belongs to the DNA polymerase type-B family.; Contains 1 CysA-type zinc finger.

Protein cellular localization

Nucleus.

Background

This gene encodes the 125-kDa catalytic subunit of DNA polymerase delta. DNA polymerase delta possesses both polymerase and 3′ to 5′ exonuclease activity and plays a critical role in DNA replication and repair. Alternatively spliced transcript variants have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 6.

Research area

All research areas>Transcription Regulators>DNA Polymerase
(View all antibody categories related to Transcription Regulators)

Note

AntibodyPlus can customize POLD1 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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