Rabbit polyclonal POLR2D antibody (A1859)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC,IF
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal POLR2D antibody (A1859)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC,IF

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200 IF 1:10 – 1:100

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit polyclonal POLR2D antibody.

Alternative names:

Check alternative names for the antibody

Expand

RBP4 antibody, RPB16 antibody, HSRBP4 antibody, HSRPB4 antibody
DNA directed RNA polymerase II 16 kDa polypeptide antibody|DNA directed RNA polymerase II subunit D antibody|DNA directed RNA polymerase II subunit RPB4 antibody|DNA-directed RNA polymerase II 16 kDa polypeptide antibody|DNA-directed RNA polymerase II subunit D antibody|DNA-directed RNA polymerase II subunit rpb4 antibody|HSRBP4 antibody|polr2d antibody|polymerase RNA II DNA directed polypeptide D antibody|RBP4 antibody|RNA polymerase II 16 kDa subunit antibody|RNA polymerase II subunit B4 antibody|RNA polymerase II subunit D antibody|RNA polymerase II subunit hsRBP4 antibody|RPB16 antibody|RPB4_HUMAN antibody|Anti-RNA polymerase II RPB4 antibody (ab186868)

SCBT cat No:

Name

Rabbit polyclonal POLR2D antibody

Catalogue No.

A1859

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human POLR2D

Host

Rabbit

Applications

WB, IHC, IF

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200
IF 1:10 – 1:100

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 16kDa/Observed: Refer to Figures

Formulation

POLR2D antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

POLR2D antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

RBP4 antibody, RPB16 antibody, HSRBP4 antibody, HSRPB4 antibody

Database links

Human UniProt/Swiss-Prot:O15514

Protein names

RBP4, RPB16, HSRBP4, HSRPB4

Protein function

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB4 is part of a subcomplex with RPB7 that binds to a pocket formed by RPB1, RPB2 and RPB6 at the base of the clamp element. The RBP4-RPB7 subcomplex seems to lock the clamp via RPB7 in the closed conformation thus preventing double-stranded DNA to enter the active site cleft. The RPB4-RPB7 subcomplex binds single-stranded DNA and RNA (By similarity).

Protein sequence and domain

Belongs to the eukaryotic RPB4 RNA polymerase subunit family.

Protein cellular localization

Nucleus .

Background

This gene encodes the fourth largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. In yeast, this polymerase subunit is associated with the polymerase under suboptimal growth conditions and may have a stress protective role. A sequence for a ribosomal pseudogene is contained within the 3′ untranslated region of the transcript from this gene.

Research area

All research areas>Transcription Regulators>POLR
(View all antibody categories related to Transcription Regulators)

Note

AntibodyPlus can customize POLR2D antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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