Rabbit polyclonal POLR2E antibody (A1755)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC,IF
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal POLR2E antibody (A1755)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC,IF

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:100 IF 1:50 – 1:200

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit polyclonal POLR2E antibody.

Alternative names:

Check alternative names for the antibody

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RPB5 antibody, XAP4 antibody, RPABC1 antibody, hRPB25 antibody, hsRPB5 antibody
and III subunit ABC1 antibody|and III subunit RPABC1 antibody|DNA directed RNA polymerase II 23 kda polypeptide antibody|DNA directed RNA polymerase II 23 kDa polypeptide antibody|DNA directed RNA polymerase II polypeptide E antibody|DNA directed RNA polymerase II subunit E antibody|DNA directed RNA polymerases I II and III subunit RPABC1 antibody|DNA-directed RNA polymerase II 23 kDa polypeptide antibody|DNA-directed RNA polymerase II subunit E antibody|DNA-directed RNA polymerases I antibody|hRPB25 antibody|hsRPB5 antibody|II antibody|Polr2e antibody|Polymerase (RNA) II (DNA directed) polypeptide E (25kD) antibody|Polymerase (RNA) II (DNA directed) polypeptide E, 25kDa antibody|RNA polymerases I antibody|RNA polymerases I, II, and III subunit ABC1 antibody|RPAB1_HUMAN antibody|RPABC1 antibody|RPB5 antibody|RPB5 homolog antibody|XAP4 antibody|Anti-POLR2E antibody [EPR11750] (ab180151)

SCBT cat No: sc-390979|sc-390902|sc-131331|

Name

Rabbit polyclonal POLR2E antibody

Catalogue No.

A1755

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human POLR2E

Host

Rabbit

Applications

WB, IHC, IF

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:100
IF 1:50 – 1:200

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 24kDa/Observed: Refer to Figures

Formulation

POLR2E antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

POLR2E antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

RPB5 antibody, XAP4 antibody, RPABC1 antibody, hRPB25 antibody, hsRPB5 antibody

Database links

Human UniProt/Swiss-Prot:P19388

Protein names

RPB5, XAP4, RPABC1, hRPB25, hsRPB5

Protein function

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. Pol II is the central component of the basal RNA polymerase II transcription machinery. Pols are composed of mobile elements that move relative to each other. In Pol II, POLR2E/RPB5 is part of the lower jaw surrounding the central large cleft and thought to grab the incoming DNA template. Seems to be the major component in this process (By similarity).

Protein sequence and domain

Belongs to the archaeal RpoH/eukaryotic RPB5 RNA polymerase subunit family.

Protein cellular localization

Nucleus .

Background

This gene encodes the fifth largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. This subunit is shared by the other two DNA-directed RNA polymerases and is present in two-fold molar excess over the other polymerase subunits. An interaction between this subunit and a hepatitis virus transactivating protein has been demonstrated, suggesting that interaction between transcriptional activators and the polymerase can occur through this subunit. A pseudogene is located on chromosome 11.

Research area

All research areas>Transcription Regulators>POLR
(View all antibody categories related to Transcription Regulators)

Note

AntibodyPlus can customize POLR2E antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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