Rabbit polyclonal PON1 antibody (A7338)

$69.00$259.00

Reactivity: Human
Applications: WB,IHC
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal PON1 antibody (A7338)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:100

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

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ESA antibody, PON antibody, MVCD5 antibody
A esterase 1 antibody|A-esterase 1 antibody|Aromatic esterase 1 antibody|Arylesterase 1 antibody|Arylesterase B type antibody|ESA antibody|Esterase A antibody|K 45 antibody|K-45 antibody|MVCD5 antibody|Paraoxonase 1 antibody|Paraoxonase antibody|Paraoxonase B type antibody|Paraoxonase, plasma antibody|Paraoxonase1 antibody|PON 1 antibody|PON antibody|PON1 antibody|PON1_HUMAN antibody|Serum aryldiakylphosphatase antibody|Serum aryldialkylphosphatase 1 antibody|Serum paraoxonase/arylesterase 1 antibody|Anti-PON1 antibody [17A12] (ab24261)

SCBT cat No: sc-59646|sc-25791|

Name

Rabbit polyclonal PON1 antibody

Catalogue No.

A7338

Reactivity

Human

Immunogen

Recombinant protein of human PON1

Host

Rabbit

Applications

WB, IHC

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:100

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 40kDa/Observed: Refer to figures

Formulation

PON1 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

PON1 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

ESA antibody, PON antibody, MVCD5 antibody

Database links

Human UniProt/Swiss-Prot:P27169

Protein names

ESA, PON, MVCD5

Protein function

Hydrolyzes the toxic metabolites of a variety of organophosphorus insecticides. Capable of hydrolyzing a broad spectrum of organophosphate substrates and lactones, and a number of aromatic carboxylic acid esters. Mediates an enzymatic protection of low density lipoproteins against oxidative modification and the consequent series of events leading to atheroma formation.

Protein tissue specificity

Plasma, associated with HDL (at protein level). Expressed in liver, but not in heart, brain, placenta, lung, skeletal muscle, kidney or pancreas.

Protein sequence and domain

Belongs to the paraoxonase family.

Protein post-translational modifications

Glycosylated.; The signal sequence is not cleaved.; Present in two forms, form B contains a disulfide bond, form A does not.

Protein cellular localization

Secreted, extracellular space.

Background

The enzyme encoded by this gene is an arylesterase that mainly hydrolyzes paroxon to produce p-nitrophenol. Paroxon is an organophosphorus anticholinesterase compound that is produced in vivo by oxidation of the insecticide parathion. Polymorphisms in this gene are a risk factor in coronary artery disease. The gene is found in a cluster of three related paraoxonase genes at 7q21.3.

Note

AntibodyPlus can customize PON1 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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