Rabbit polyclonal PON2 antibody (A1646)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal PON2 antibody (A1646)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

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A esterase 2 antibody|A-esterase 2 antibody|Aromatic esterase 2 antibody|Paraoxonase 2 antibody|Paraoxonase nirs antibody|PON 2 antibody|PON2 antibody|PON2_HUMAN antibody|Serum aryldialkylphosphatase 2 antibody|Serum paraoxonase/arylesterase 2 antibody|Anti-PON2 antibody [EPR15295] (ab183710)

SCBT cat No: sc-66578|sc-374158|sc-373981|

Name

Rabbit polyclonal PON2 antibody

Catalogue No.

A1646

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human PON2

Host

Rabbit

Applications

WB, IHC

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 39kDa/Observed: Refer to figures

Formulation

PON2 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

PON2 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Database links

Human UniProt/Swiss-Prot:Q15165

Protein function

Capable of hydrolyzing lactones and a number of aromatic carboxylic acid esters. Has antioxidant activity. Is not associated with high density lipoprotein. Prevents LDL lipid peroxidation, reverses the oxidation of mildly oxidized LDL, and inhibits the ability of MM-LDL to induce monocyte chemotaxis.

Protein tissue specificity

Widely expressed with highest expression in liver, lung, placenta, testis and heart.

Protein sequence and domain

Belongs to the paraoxonase family.

Protein post-translational modifications

The signal sequence is not cleaved.

Protein cellular localization

Membrane ; Peripheral membrane protein .

Background

This gene encodes a member of the paraoxonase gene family, which includes three known members located adjacent to each other on the long arm of chromosome 7. The encoded protein is ubiquitously expressed in human tissues, membrane-bound, and may act as a cellular antioxidant, protecting cells from oxidative stress. Hydrolytic activity against acylhomoserine lactones, important bacterial quorum-sensing mediators, suggests the encoded protein may also play a role in defense responses to pathogenic bacteria. Mutations in this gene may be associated with vascular disease and a number of quantitative phenotypes related to diabetes. Alternatively spliced transcript variants encoding different isoforms have been described.

Note

AntibodyPlus can customize PON2 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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