Rabbit polyclonal POU2F1 antibody (A1682)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal POU2F1 antibody (A1682)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit polyclonal POU2F1 antibody.

Alternative names:

Check alternative names for the antibody

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OCT1 antibody, OTF1 antibody
FLJ42836 antibody|NF A1 antibody|NF-A1 antibody|Oct 1 antibody|Oct 1B antibody|Oct-1 antibody|OCT1 antibody|Octamer binding protein 1 antibody|Octamer binding transcription factor 1 antibody|Octamer-binding protein 1 antibody|Octamer-binding transcription factor 1 antibody|OTF 1 antibody|OTF-1 antibody|OTF1 antibody|OTTHUMP00000032348 antibody|OTTHUMP00000032350 antibody|OTTHUMP00000032351 antibody|PO21 antibody|PO2F1 antibody|PO2F1_HUMAN antibody|POU class 2 homeobox 1 antibody|POU domain class 2 transcription factor 1 antibody|POU domain, class 2, transcription factor 1 antibody|POU2F1 antibody|Anti-Oct-1 antibody [EPR16570] (ab178869)

SCBT cat No: sc-71744|sc-8024|sc-293181|sc-232|sc-28334|sc-25399|

Name

Rabbit polyclonal POU2F1 antibody

Catalogue No.

A1682

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human POU2F1

Host

Rabbit

Applications

WB, IHC

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 76kDa/Observed: Refer to Figures

Formulation

POU2F1 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

POU2F1 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

OCT1 antibody, OTF1 antibody

Database links

Human UniProt/Swiss-Prot:P14859

Protein names

OCT1, OTF1

Protein function

Transcription factor that binds to the octamer motif (5′-ATTTGCAT-3′) and activates the promoters of the genes for some small nuclear RNAs (snRNA) and of genes such as those for histone H2B and immunoglobulins. Modulates transcription transactivation by NR3C1, AR and PGR (By similarity). In case of human herpes simplex virus (HSV) infection, POU2F1 forms a multiprotein-DNA complex with the viral transactivator protein VP16 and HCFC1 thereby enabling the transcription of the viral immediate early genes.

Protein tissue specificity

Ubiquitous. Isoform 2 is lymphocyte-specific.

Protein sequence and domain

Belongs to the POU transcription factor family. Class-2 subfamily.; Contains 1 homeobox DNA-binding domain.; Contains 1 POU-specific domain.

Protein post-translational modifications

Phosphorylated by PRKDC.

Protein cellular localization

Nucleus.

Background

Oct-1 (POU2F1) is a ubiquitously expressed, octamer-binding transcription factor containing a POU domain with a homeobox subdomain (1). Oct-1 has been shown to interact with several transcription factors in mediating specific gene expression, including SNAPc (2), OBF-1 (a B-cell transcriptional coactivator protein) (3), TFIIB (4), and TBP (TATA-box-binding protein) (5). Its POU DNA-binding domain allows Oct-1 the flexibility to facilitate the binding and recruitment of several tissue-specific cofactors to either positively or negatively regulate a variety of genes, exerting an important role in development (6).

Research area

All research areas>Homeodomain Proteins>Oct
(View all antibody categories related to Homeodomain Proteins)

Note

AntibodyPlus can customize POU2F1 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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