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Rabbit polyclonal POU2F1 antibody (A1682)
Supplier: ABclonal Inc.
Recommended applications: WB,IHC
WB 1:500 – 1:2000 IHC 1:50 – 1:200
Recommended protocols: check protocols
Click or hover above images to see image description for Rabbit polyclonal POU2F1 antibody.
Check alternative names for the antibodyExpand
OCT1 antibody, OTF1 antibody
FLJ42836 antibody|NF A1 antibody|NF-A1 antibody|Oct 1 antibody|Oct 1B antibody|Oct-1 antibody|OCT1 antibody|Octamer binding protein 1 antibody|Octamer binding transcription factor 1 antibody|Octamer-binding protein 1 antibody|Octamer-binding transcription factor 1 antibody|OTF 1 antibody|OTF-1 antibody|OTF1 antibody|OTTHUMP00000032348 antibody|OTTHUMP00000032350 antibody|OTTHUMP00000032351 antibody|PO21 antibody|PO2F1 antibody|PO2F1_HUMAN antibody|POU class 2 homeobox 1 antibody|POU domain class 2 transcription factor 1 antibody|POU domain, class 2, transcription factor 1 antibody|POU2F1 antibody|Anti-Oct-1 antibody [EPR16570] (ab178869)
SCBT cat No: sc-71744|sc-8024|sc-293181|sc-232|sc-28334|sc-25399|
Rabbit polyclonal POU2F1 antibody
|Catalogue No.|| |
Human, Mouse, Rat
Recombinant protein of human POU2F1
|Recommended dilution|| |
WB 1:500 – 1:2000
|Molecular weight|| |
Predicted: 76kDa/Observed: Refer to Figures
POU2F1 antibody was tube-contained.
POU2F1 antibody was purified using affinity purification.
Store at -20 Celsius degree. Avoid freeze / thaw cycles.
|Alternative antibody names|| |
OCT1 antibody, OTF1 antibody
|Database links|| |
|Protein names|| |
|Protein function|| |
Transcription factor that binds to the octamer motif (5′-ATTTGCAT-3′) and activates the promoters of the genes for some small nuclear RNAs (snRNA) and of genes such as those for histone H2B and immunoglobulins. Modulates transcription transactivation by NR3C1, AR and PGR (By similarity). In case of human herpes simplex virus (HSV) infection, POU2F1 forms a multiprotein-DNA complex with the viral transactivator protein VP16 and HCFC1 thereby enabling the transcription of the viral immediate early genes.
|Protein tissue specificity|| |
Ubiquitous. Isoform 2 is lymphocyte-specific.
|Protein sequence and domain|| |
Belongs to the POU transcription factor family. Class-2 subfamily.; Contains 1 homeobox DNA-binding domain.; Contains 1 POU-specific domain.
|Protein post-translational modifications|| |
Phosphorylated by PRKDC.
|Protein cellular localization|| |
Oct-1 (POU2F1) is a ubiquitously expressed, octamer-binding transcription factor containing a POU domain with a homeobox subdomain (1). Oct-1 has been shown to interact with several transcription factors in mediating specific gene expression, including SNAPc (2), OBF-1 (a B-cell transcriptional coactivator protein) (3), TFIIB (4), and TBP (TATA-box-binding protein) (5). Its POU DNA-binding domain allows Oct-1 the flexibility to facilitate the binding and recruitment of several tissue-specific cofactors to either positively or negatively regulate a variety of genes, exerting an important role in development (6).
AntibodyPlus can customize POU2F1 antibody according to your requirement, including bulk product size,etc. Please contact firstname.lastname@example.org. AntibodyPlus provides antibody trial sample for your own antibody validation.
|Product type|| |
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