Rabbit polyclonal PPARD antibody (A5656)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC,IF
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal PPARD antibody (A5656)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC,IF

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200 IF 1:50 – 1:200

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit polyclonal PPARD antibody.

Alternative names:

Check alternative names for the antibody

Expand

FAAR antibody, NUC1 antibody, NUCI antibody, NR1C2 antibody, NUCII antibody, PPARB antibody
FAAR antibody|MGC3931 antibody|NR1C2 antibody|NUC1 antibody|NUCI antibody|NUCII antibody|Nuclear hormone receptor 1 antibody|Nuclear receptor subfamily 1 group C member 2 antibody|Peroxisome proliferative activated receptor delta antibody|Peroxisome proliferator-activated receptor beta (PPAR-beta) antibody|Peroxisome proliferator-activated receptor beta antibody|Peroxisome proliferator-activated receptor delta antibody|PPAR beta antibody|PPAR-beta antibody|PPAR-delta antibody|PPAR-? antibody|PPARB antibody|ppard antibody|PPARD_HUMAN antibody|Anti-PPAR delta antibody (ab23673)

SCBT cat No: sc-74517|sc-74440|sc-7197|sc-1987|sc-1986|

Name

Rabbit polyclonal PPARD antibody

Catalogue No.

A5656

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human PPARD

Host

Rabbit

Applications

WB, IHC, IF

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200
IF 1:50 – 1:200

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 49kDa/Observed: Refer to Figures

Formulation

PPARD antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

PPARD antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

FAAR antibody, NUC1 antibody, NUCI antibody, NR1C2 antibody, NUCII antibody, PPARB antibody

Database links

Human UniProt/Swiss-Prot:Q03181

Protein names

FAAR, NUC1, NUCI, NR1C2, NUCII, PPARB

Protein function

Ligand-activated transcription factor. Receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Has a preference for poly-unsaturated fatty acids, such as gamma-linoleic acid and eicosapentanoic acid. Once activated by a ligand, the receptor binds to promoter elements of target genes. Regulates the peroxisomal beta-oxidation pathway of fatty acids. Functions as transcription activator for the acyl-CoA oxidase gene. Decreases expression of NPC1L1 once activated by a ligand.

Protein tissue specificity

Ubiquitous with maximal levels in placenta and skeletal muscle.

Protein sequence and domain

Belongs to the nuclear hormone receptor family. NR1 subfamily.; Contains 1 nuclear receptor DNA-binding domain.

Protein cellular localization

Nucleus.

Background

This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) family. PPARs are nuclear hormone receptors that bind peroxisome proliferators and control the size and number of peroxisomes produced by cells. PPARs mediate a variety of biological processes, and may be involved in the development of several chronic diseases, including diabetes, obesity, atherosclerosis, and cancer. This protein is a potent inhibitor of ligand-induced transcription activity of PPAR alpha and PPAR gamma. It may function as an integrator of transcription repression and nuclear receptor signaling. The expression of this gene is found to be elevated in colorectal cancer cells. The elevated expression can be repressed by adenomatosis polyposis coli (APC), a tumor suppressor protein related to APC/beta-catenin signaling pathway. Knockout studies in mice suggested the role of this protein in myelination of the corpus callosum, lipid metabolism, and epidermal cell proliferation. Alternate splicing results in multiple transcript variants.

Research area

All research areas>Steroid Receptors>PPAR
(View all antibody categories related to Steroid Receptors)

Note

AntibodyPlus can customize PPARD antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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