Rabbit polyclonal PPID antibody (A6949)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC,IF
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal PPID antibody (A6949)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC,IF

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200 IF 1:50 – 1:100

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

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CYPD antibody, CYP-40 antibody
40 kDa peptidyl prolyl cis trans isomerase antibody|Cyclophilin-40 antibody|Cyclophilin40 antibody|CyclophilinD antibody|CYP 40 antibody|CYP-40 antibody|CYP40 antibody|CYPD antibody|MGC33096 antibody|Peptidyl Prolyl Isomerase D antibody|Peptidyl-prolyl cis-trans isomerase D antibody|Peptidylprolyl isomerase D antibody|PPIase antibody|PPIase D antibody|Ppid antibody|PPID_HUMAN antibody|Rotamase antibody|Rotamase D antibody|Anti-Cyclophilin 40 antibody (ab3562)

SCBT cat No: sc-137216|sc-33068|sc-137157|sc-66848|sc-137136|

Name

Rabbit polyclonal PPID antibody

Catalogue No.

A6949

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human PPID

Host

Rabbit

Applications

WB, IHC, IF

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200
IF 1:50 – 1:100

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 41kDa/Observed: Refer to figures

Formulation

PPID antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

PPID antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

CYPD antibody, CYP-40 antibody

Database links

Human UniProt/Swiss-Prot:Q08752

Protein names

CYPD, CYP-40

Protein function

PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Proposed to act as a co-chaperone in HSP90 complexes such as in unligated steroid receptors heterocomplexes. Different co-chaperones seem to compete for association with HSP90 thus establishing distinct HSP90-co-chaperone-receptor complexes with the potential to exert tissue-specific receptor activity control. May have a preference for estrogen receptor complexes and is not found in glucocorticoid receptor complexes. May be involved in cytoplasmic dynein-dependent movement of the receptor from the cytoplasm to the nucleus. May regulate MYB by inhibiting its DNA-binding activity. Involved in regulation of AHR signaling by promoting the formation of the AHR:ARNT dimer; the function is independent of HSP90 but requires the chaperone activity. Involved in regulation of UV radiation-induced apoptosis. Promotes cell viability in anaplastic lymphoma kinase-positive anaplastic large-cell lymphoma (ALK+ ALCL) cell lines. May be involved in hepatitis C virus (HCV) replication and release.

Protein tissue specificity

Widely expressed.

Protein sequence and domain

Belongs to the cyclophilin-type PPIase family. PPIase D subfamily.; Contains 1 PPIase cyclophilin-type domain.; Contains 3 TPR repeats.

Protein cellular localization

Cytoplasm . Nucleus, nucleolus . Nucleus, nucleoplasm .

Background

The protein encoded by this gene is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. This protein has been shown to possess PPIase activity and, similar to other family members, can bind to the immunosuppressant cyclosporin A.

Research area

All research areas>Signaling Intermediates>Cyclophilin
(View all antibody categories related to Signaling Intermediates)

Note

AntibodyPlus can customize PPID antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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