Rabbit polyclonal PPP1CB antibody (A1088)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC,IF
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal PPP1CB antibody (A1088)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC,IF

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200 IF 1:50 – 1:200

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit polyclonal PPP1CB antibody.

Alternative names:

Check alternative names for the antibody

Expand

PPP1CB antibody,MGC3672 antibody,PP-1B antibody,PPP1CD antibody
MGC3672 antibody|PP 1B antibody|PP-1B antibody|PP1B antibody|PP1B_HUMAN antibody|PP1beta antibody|PPP1CB antibody|PPP1CD antibody|Protein phosphatase 1 beta antibody|Protein phosphatase 1 catalytic subunit beta isoform antibody|Protein phosphatase 1 delta antibody|Protein phosphatase 1, catalytic subunit, beta isozyme antibody|Protein phosphatase 1, catalytic subunit, delta isoform antibody|Serine threonine protein phosphatase PP1 beta catalytic subunit antibody|Serine/threonine-protein phosphatase PP1-beta catalytic subunit antibody|Anti-Protein Phosphatase 1 beta antibody [EP1804Y] (ab53315)

SCBT cat No: sc-517233|sc-365678|sc-6106|sc-373782|sc-377125|sc-373783|sc-6107|

Name

Rabbit polyclonal PPP1CB antibody

Catalogue No.

A1088

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human PPP1CB

Host

Rabbit

Applications

WB, IHC, IF

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200
IF 1:50 – 1:200

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 37kDa/Observed: Refer to Figures

Formulation

PPP1CB antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

PPP1CB antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

PPP1CB antibody,MGC3672 antibody,PP-1B antibody,PPP1CD antibody

Database links

Human UniProt/Swiss-Prot:P62140

Protein names

PPP1CB,MGC3672,PP-1B,PPP1CD

Protein function

Protein phosphatase that associates with over 200 regulatory proteins to form highly specific holoenzymes which dephosphorylate hundreds of biological targets. Protein phosphatase (PP1) is essential for cell division, it participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. Involved in regulation of ionic conductances and long-term synaptic plasticity. Component of the PTW/PP1 phosphatase complex, which plays a role in the control of chromatin structure and cell cycle progression during the transition from mitosis into interphase. In balance with CSNK1D and CSNK1E, determines the circadian period length, through the regulation of the speed and rhythmicity of PER1 and PER2 phosphorylation. May dephosphorylate CSNK1D and CSNK1E. Dephosphorylates the ‘Ser-418’ residue of FOXP3 in regulatory T-cells (Treg) from patients with rheumatoid arthritis, thereby inactivating FOXP3 and rendering Treg cells functionally defective .

Protein sequence and domain

Belongs to the PPP phosphatase family. PP-1 subfamily.

Protein cellular localization

Cytoplasm . Nucleus . Nucleus, nucleoplasm . Nucleus, nucleolus . Note: Highly mobile in cells and can be relocalized through interaction with targeting subunits. In the presence of PPP1R8 relocalizes from the nucleus to nuclear speckles.

Background

Protein phosphatase 1 (PP1) is the main eukaryotic protein serine/threonine phosphatase that regulates an enormous variety of cellular processes including protein-protein interactions, gene transcription, cell-cycle progression and apoptosis. It is a trimeric complex composed of a regulatory subunit, a variable subunit and a catalytic subunit. The catalytic subunit of PP1 (PP1c) can interact with amount of regulatory subunits in vivo that target it to particular subcellular locations and regulate its activity towards specific substrates. PPP1CB migrated as a 37kd protein on SDS page.

Research area

All research areas>Kinases and Phosphatases>PP1
(View all antibody categories related to Kinases and Phosphatases)

Note

AntibodyPlus can customize PPP1CB antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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