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Rabbit polyclonal PPP2CB antibody (A3122)
Supplier: ABclonal Inc.
Recommended applications: WB,IHC
WB 1:500 – 1:2000 IHC 1:50 – 1:200
Recommended protocols: check protocols
Click or hover above images to see image description for Rabbit polyclonal PPP2CB antibody.
Check alternative names for the antibodyExpand
PP2CB antibody, PP2Abeta antibody
PP2A beta antibody|PP2A-beta antibody|PP2AB_HUMAN antibody|PP2Abeta antibody|PP2CB antibody|Ppp2cb antibody|Protein phosphatase 2 (formerly 2A), catalytic subunit, beta isoform antibody|Protein phosphatase 2 catalytic subunit beta isozyme antibody|Protein phosphatase 2, catalytic subunit, beta isoform antibody|Protein phosphatase 2A catalytic subunit beta isoform antibody|Protein phosphatase type 2A catalytic subunit antibody|Serine/threonine protein phosphatase 2A catalytic subunit beta antibody|Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform antibody|Anti-PPP2CB antibody [EPR11786(B)] (ab168371)
SCBT cat No: sc-80990|
Rabbit polyclonal PPP2CB antibody
|Catalogue No.|| |
Human, Mouse, Rat
A synthetic peptide of human PPP2CB
|Recommended dilution|| |
WB 1:500 – 1:2000
|Molecular weight|| |
Predicted: 36kDa/Observed: Refer to Figures
PPP2CB antibody was tube-contained.
PPP2CB antibody was purified using affinity purification.
Store at -20 Celsius degree. Avoid freeze / thaw cycles.
|Alternative antibody names|| |
PP2CB antibody, PP2Abeta antibody
|Database links|| |
|Protein names|| |
|Protein function|| |
PP2A can modulate the activity of phosphorylase B kinase casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase.
|Protein sequence and domain|| |
Belongs to the PPP phosphatase family. PP-1 subfamily.
|Protein post-translational modifications|| |
Reversibly methyl esterified on Leu-309 by leucine carboxyl methyltransferase 1 (LCMT1) and protein phosphatase methylesterase 1 (PPME1). Carboxyl methylation influences the affinity of the catalytic subunit for the different regulatory subunits, thereby modulating the PP2A holoenzyme’s substrate specificity, enzyme activity and cellular localization.; Phosphorylation of either threonine (by autophosphorylation-activated protein kinase) or tyrosine results in inactivation of the phosphatase. Auto-dephosphorylation has been suggested as a mechanism for reactivation.; May be monoubiquitinated by NOSIP.
|Protein cellular localization|| |
Cytoplasm . Nucleus . Chromosome, centromere . Cytoplasm, cytoskeleton, spindle pole . Note: In prometaphase cells, but not in anaphase cells, localizes at centromeres. During mitosis, also found at spindle poles.
This gene encodes the phosphatase 2A catalytic subunit. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. This gene encodes a beta isoform of the catalytic subunit.
AntibodyPlus can customize PPP2CB antibody according to your requirement, including bulk product size,etc. Please contact firstname.lastname@example.org. AntibodyPlus provides antibody trial sample for your own antibody validation.
|Product type|| |
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