Rabbit polyclonal PPP2CB antibody (A3122)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal PPP2CB antibody (A3122)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit polyclonal PPP2CB antibody.

Alternative names:

Check alternative names for the antibody

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PP2CB antibody, PP2Abeta antibody
PP2A beta antibody|PP2A-beta antibody|PP2AB_HUMAN antibody|PP2Abeta antibody|PP2CB antibody|Ppp2cb antibody|Protein phosphatase 2 (formerly 2A), catalytic subunit, beta isoform antibody|Protein phosphatase 2 catalytic subunit beta isozyme antibody|Protein phosphatase 2, catalytic subunit, beta isoform antibody|Protein phosphatase 2A catalytic subunit beta isoform antibody|Protein phosphatase type 2A catalytic subunit antibody|Serine/threonine protein phosphatase 2A catalytic subunit beta antibody|Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform antibody|Anti-PPP2CB antibody [EPR11786(B)] (ab168371)

SCBT cat No: sc-80990|

Name

Rabbit polyclonal PPP2CB antibody

Catalogue No.

A3122

Reactivity

Human, Mouse, Rat

Immunogen

A synthetic peptide of human PPP2CB

Host

Rabbit

Applications

WB, IHC

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 36kDa/Observed: Refer to Figures

Formulation

PPP2CB antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

PPP2CB antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

PP2CB antibody, PP2Abeta antibody

Database links

Human UniProt/Swiss-Prot:P62714

Protein names

PP2CB, PP2Abeta

Protein function

PP2A can modulate the activity of phosphorylase B kinase casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase.

Protein sequence and domain

Belongs to the PPP phosphatase family. PP-1 subfamily.

Protein post-translational modifications

Reversibly methyl esterified on Leu-309 by leucine carboxyl methyltransferase 1 (LCMT1) and protein phosphatase methylesterase 1 (PPME1). Carboxyl methylation influences the affinity of the catalytic subunit for the different regulatory subunits, thereby modulating the PP2A holoenzyme’s substrate specificity, enzyme activity and cellular localization.; Phosphorylation of either threonine (by autophosphorylation-activated protein kinase) or tyrosine results in inactivation of the phosphatase. Auto-dephosphorylation has been suggested as a mechanism for reactivation.; May be monoubiquitinated by NOSIP.

Protein cellular localization

Cytoplasm . Nucleus . Chromosome, centromere . Cytoplasm, cytoskeleton, spindle pole . Note: In prometaphase cells, but not in anaphase cells, localizes at centromeres. During mitosis, also found at spindle poles.

Background

This gene encodes the phosphatase 2A catalytic subunit. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. This gene encodes a beta isoform of the catalytic subunit.

Research area

All research areas>Kinases and Phosphatases>PP2
(View all antibody categories related to Kinases and Phosphatases)

Note

AntibodyPlus can customize PPP2CB antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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