Rabbit polyclonal PRDM6 antibody (A7846)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal PRDM6 antibody (A7846)

Supplier: ABclonal Inc.

Recommended applications: WB

Recommended dilution:

WB 1:500 – 1:2000

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit polyclonal PRDM6 antibody.

Alternative names:

Check alternative names for the antibody

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Gm92 antibody|PFM3 antibody|PR domain containing 6 antibody|PR domain containing protein 6 antibody|PR domain zinc finger protein 6 antibody|PR domain-containing protein 6 antibody|Prdm6 antibody|PRDM6_HUMAN antibody|PRISM antibody|Putative histone-lysine N-methyltransferase PRDM6 antibody|RGD1559594 antibody|Anti-PRDM6 antibody (ab123317)

SCBT cat No: sc-98736|sc-107065|

Name

Rabbit polyclonal PRDM6 antibody

Catalogue No.

A7846

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human PRDM6

Host

Rabbit

Applications

WB

Recommended dilution

WB 1:500 – 1:2000

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 64kDa/Observed: Refer to figures

Formulation

PRDM6 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

PRDM6 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Database links

Human UniProt/Swiss-Prot:Q9NQX0

Protein function

Putative histone methyltransferase that acts as a transcriptional repressor of smooth muscle gene expression. Promotes the transition from differentiated to proliferative smooth muscle by suppressing differentiation and maintaining the proliferative potential of vascular smooth muscle cells. Also plays a role in endothelial cells by inhibiting endothelial cell proliferation, survival and differentiation. It is unclear whether it has histone methyltransferase activity in vivo. According to some authors, it does not act as a histone methyltransferase by itself and represses transcription by recruiting EHMT2/G9a. According to others, it possesses histone methyltransferase activity when associated with other proteins and specifically methylates ‘Lys-20’ of histone H4 in vitro. ‘Lys-20’ methylation represents a specific tag for epigenetic transcriptional repression (By similarity).

Protein sequence and domain

Belongs to the class V-like SAM-binding methyltransferase superfamily.; Contains 4 C2H2-type zinc fingers.; Contains 1 SET domain.

Protein cellular localization

Nucleus .

Research area

All research areas>Transcription Regulators>PRDM
(View all antibody categories related to Transcription Regulators)

Note

AntibodyPlus can customize PRDM6 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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