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Rabbit polyclonal PRDM6 antibody (A7846)
Supplier: ABclonal Inc.
Recommended applications: WB
WB 1:500 – 1:2000
Recommended protocols: check protocols
Click or hover above images to see image description for Rabbit polyclonal PRDM6 antibody.
Check alternative names for the antibodyExpand
Gm92 antibody|PFM3 antibody|PR domain containing 6 antibody|PR domain containing protein 6 antibody|PR domain zinc finger protein 6 antibody|PR domain-containing protein 6 antibody|Prdm6 antibody|PRDM6_HUMAN antibody|PRISM antibody|Putative histone-lysine N-methyltransferase PRDM6 antibody|RGD1559594 antibody|Anti-PRDM6 antibody (ab123317)
SCBT cat No: sc-98736|sc-107065|
Rabbit polyclonal PRDM6 antibody
|Catalogue No.|| |
Human, Mouse, Rat
Recombinant protein of human PRDM6
|Recommended dilution|| |
WB 1:500 – 1:2000
|Molecular weight|| |
Predicted: 64kDa/Observed: Refer to figures
PRDM6 antibody was tube-contained.
PRDM6 antibody was purified using affinity purification.
Store at -20 Celsius degree. Avoid freeze / thaw cycles.
|Database links|| |
|Protein function|| |
Putative histone methyltransferase that acts as a transcriptional repressor of smooth muscle gene expression. Promotes the transition from differentiated to proliferative smooth muscle by suppressing differentiation and maintaining the proliferative potential of vascular smooth muscle cells. Also plays a role in endothelial cells by inhibiting endothelial cell proliferation, survival and differentiation. It is unclear whether it has histone methyltransferase activity in vivo. According to some authors, it does not act as a histone methyltransferase by itself and represses transcription by recruiting EHMT2/G9a. According to others, it possesses histone methyltransferase activity when associated with other proteins and specifically methylates ‘Lys-20’ of histone H4 in vitro. ‘Lys-20’ methylation represents a specific tag for epigenetic transcriptional repression (By similarity).
|Protein sequence and domain|| |
Belongs to the class V-like SAM-binding methyltransferase superfamily.; Contains 4 C2H2-type zinc fingers.; Contains 1 SET domain.
|Protein cellular localization|| |
AntibodyPlus can customize PRDM6 antibody according to your requirement, including bulk product size,etc. Please contact email@example.com. AntibodyPlus provides antibody trial sample for your own antibody validation.
|Product type|| |
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