Rabbit polyclonal PRG2 antibody (A2532)

$69.00$259.00

Reactivity: Human,Mouse
Applications: WB,IHC
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal PRG2 antibody (A2532)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

Expand

MBP antibody, BMPG antibody, MBP1 antibody
BMPG antibody|Bone marrow proteoglycan antibody|EMBP antibody|Eosinophil granule major basic protein antibody|Eosinophil major basic protein antibody|MBP antibody|MBP1 antibody|MGC14537 antibody|Natural killer cell activator antibody|Pregnancy associated major basic protein antibody|Pregnancy-associated major basic protein antibody|PRG 2 antibody|PRG2 antibody|PRG2_HUMAN antibody|Proteoglycan 2 antibody|Proteoglycan 2 bone marrow antibody|Proteoglycan 2 preproprotein antibody|Proteoglycan2 antibody|Anti-Major Basic Protein antibody (ab187523)

SCBT cat No: sc-59163|sc-34012|sc-59164|sc-365702|sc-365701|sc-33557|

Name

Rabbit polyclonal PRG2 antibody

Catalogue No.

A2532

Reactivity

Human, Mouse

Immunogen

Recombinant protein of human PRG2

Host

Rabbit

Applications

WB, IHC

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 25kDa/Observed: Refer to Figures

Formulation

PRG2 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

PRG2 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

MBP antibody, BMPG antibody, MBP1 antibody

Database links

Human UniProt/Swiss-Prot:P13727

Protein names

MBP, BMPG, MBP1

Protein function

Cytotoxin and helminthotoxin. Also induces non-cytolytic histamine release from human basophils. Involved in antiparasitic defense mechanisms and immune hypersensitivity reactions. The proform acts as a proteinase inhibitor, reducing the activity of PAPPA.

Protein tissue specificity

High levels of the proform in placenta and pregnancy serum; in placenta, localized to X cells of septa and anchoring villi. Lower levels in a variety of other tissues including kidney, myometrium, endometrium, ovaries, breast, prostate, bone marrow and colon.

Protein sequence and domain

Contains 1 C-type lectin domain.

Protein post-translational modifications

Nitrated.

Protein cellular localization

Bone marrow proteoglycan: Secreted. Note: The proform is secreted.; Eosinophil granule major basic protein: Cytoplasmic vesicle, secretory vesicle. Note: The proform is secreted. The mature protein is found in the matrix of the eosinophil’s large specific granule (crystalloid core).

Background

The protein encoded by this gene is the predominant constituent of the crystalline core of the eosinophil granule. High levels of the proform of this protein are also present in placenta and pregnancy serum, where it exists as a complex with several other proteins including pregnancy-associated plasma protein A (PAPPA), angiotensinogen (AGT), and C3dg. This protein may be involved in antiparasitic defense mechanisms as a cytotoxin and helminthotoxin, and in immune hypersensitivity reactions. It is directly implicated in epithelial cell damage, exfoliation, and bronchospasm in allergic diseases. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Note

AntibodyPlus can customize PRG2 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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