Rabbit polyclonal PRPF3 antibody (A5482)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC,IF
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal PRPF3 antibody (A5482)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC,IF

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200 IF 1:50 – 1:200

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit polyclonal PRPF3 antibody.

Alternative names:

Check alternative names for the antibody

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PRP3 antibody, RP18 antibody, HPRP3 antibody, Prp3p antibody, HPRP3P antibody, SNRNP90 antibody
hPrp3 antibody|HPRP3P antibody|Pre mRNA splicing factor 3 antibody|Pre-mRNA-splicing factor 3 antibody|Precursor mRNA-processing factor 3, S. crevisiae, homolog of antibody|PRP3 pre-mRNA processing factor 3 homolog (S. cerevisiae) antibody|Prp3p antibody|PRPF3 antibody|PRPF3_HUMAN antibody|RP18 antibody|SNRNP90 antibody|U4/U6 small nuclear ribonucleoprotein PRP3 antibody|U4/U6 snRNP 90 kDa protein antibody|Anti-PRPF3 antibody (ab187535)

SCBT cat No: sc-101130|sc-102068|

Name

Rabbit polyclonal PRPF3 antibody

Catalogue No.

A5482

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human PRPF3

Host

Rabbit

Applications

WB, IHC, IF

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200
IF 1:50 – 1:200

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 78kDa/Observed: Refer to Figures

Formulation

PRPF3 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

PRPF3 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

PRP3 antibody, RP18 antibody, HPRP3 antibody, Prp3p antibody, HPRP3P antibody, SNRNP90 antibody

Database links

Human UniProt/Swiss-Prot:O43395

Protein names

PRP3, RP18, HPRP3, Prp3p, HPRP3P, SNRNP90

Protein function

Participates in pre-mRNA splicing. Part of the U4/U5/U6 tri-snRNP complex, one of the building blocks of the spliceosome.

Protein tissue specificity

Highly expressed in retina, liver, kidney and blood. Detected at lower levels in heart and brain.

Protein sequence and domain

Contains 1 PWI domain.

Protein post-translational modifications

Ubiquitinated. Undergoes ‘Lys-63’-linked polyubiquitination by PRPF19 and deubiquitination by USP4. ‘Lys-63’-linked ubiquitination increases the affinity for PRPF8 and may regulate the assembly of the U4/U6-U5 tri-snRNP complex.

Protein cellular localization

Nucleus speckle. Note: Colocalizes with spliceosomal snRNPs.

Background

The removal of introns from nuclear pre-mRNAs occurs on complexes called spliceosomes, which are made up of 4 small nuclear ribonucleoprotein (snRNP) particles and an undefined number of transiently associated splicing factors. This gene product is one of several proteins that associate with U4 and U6 snRNPs. Mutations in this gene are associated with retinitis pigmentosa-18.

Research area

All research areas>Transcription Regulators>PRPF
(View all antibody categories related to Transcription Regulators)

Note

AntibodyPlus can customize PRPF3 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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