Rabbit polyclonal PRSS2 antibody (A7923)

$69.00$259.00

Reactivity: Human,Mouse
Applications: WB,IHC
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal PRSS2 antibody (A7923)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit polyclonal PRSS2 antibody.

Alternative names:

Check alternative names for the antibody

Expand

TRY2 antibody, TRY8 antibody, TRYP2 antibody
Anionic trypsinogen antibody|EC 3.4.21.4 antibody|MGC111183 antibody|MGC120174 antibody|Protease serine 2 preproprotein antibody|Protease, serine, 2 (trypsin 2) antibody|Protease, serine, 2 antibody|Protease, serine, 2, preproprotein antibody|Prss2 antibody|Serine protease 2 antibody|TRY2 antibody|TRY2_HUMAN antibody|TRY8 antibody|TRYP2 antibody|Trypsin 2 antibody|Trypsin II antibody|Trypsin-2 antibody|Trypsinogen 2 antibody|Anti-PRSS2 antibody (ab76781)

SCBT cat No:

Name

Rabbit polyclonal PRSS2 antibody

Catalogue No.

A7923

Reactivity

Human, Mouse

Immunogen

Recombinant protein of human PRSS2

Host

Rabbit

Applications

WB, IHC

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 26kDa/Observed: Refer to figures

Formulation

PRSS2 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

PRSS2 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

TRY2 antibody, TRY8 antibody, TRYP2 antibody

Database links

Human UniProt/Swiss-Prot:P07478

Protein names

TRY2, TRY8, TRYP2

Protein function

In the ileum, may be involved in defensin processing, including DEFA5.

Protein tissue specificity

Expressed in Paneth cells, at the base of small intestinal crypts.

Protein sequence and domain

Belongs to the peptidase S1 family.; Contains 1 peptidase S1 domain.

Protein post-translational modifications

Sulfated on tyrosine.; Sulfation at Tyr-154 increases selectivity towards basic versus apolar residues at the P2′ position of inhibitors that bind in a substrate-like fashion. Although the increase in selectivity is relatively small, it may facilitate digestion of a broader range of dietary proteins.

Protein cellular localization

Secreted, extracellular space.

Background

This gene belongs to the trypsin family of serine proteases and encodes anionic trypsinogen. It is part of a cluster of trypsinogen genes that are located within the T cell receptor beta locus. Enzymes of this family cleave peptide bonds that follow lysine or arginine residues. This protein is found at high levels in pancreatic juice and its upregulation is a characteristic feature of pancreatitis. This protein has also been found to activate pro-urokinase in ovarian tumors, suggesting a function in tumor invasion. In addition, this enzyme is able to cleave across the type II collagen triple helix in rheumatoid arthritis synovitis tissue, potentially participating in the degradation of type II collagen-rich cartilage matrix. Alternative splicing results in multiple transcript variants.

Note

AntibodyPlus can customize PRSS2 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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