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Rabbit polyclonal PSMB3 antibody (A9947)
Supplier: ABclonal Inc.
Recommended applications: WB
WB 1:500 – 1:2000
Recommended protocols: check protocols
Click or hover above images to see image description for Rabbit polyclonal PSMB3 antibody.
Check alternative names for the antibodyExpand
C10 II antibody|HC10 II antibody|proteasome (prosome, macropain) subunit, beta type 3 antibody|Proteasome beta 3 subunit antibody|Proteasome chain 13 antibody|proteasome component C10 II antibody|Proteasome component C10-II antibody|Proteasome subunit beta type-3 antibody|Proteasome theta chain antibody|PSB3_HUMAN antibody|PSMB3 antibody|Anti-Proteasome 20S beta 3 antibody (ab140458)
SCBT cat No: sc-55005|sc-58411|
Rabbit polyclonal PSMB3 antibody
|Catalogue No.|| |
Human, Mouse, Rat
Recombinant protein of human PSMB3
|Recommended dilution|| |
WB 1:500 – 1:2000
|Molecular weight|| |
Predicted: 23kDa/Observed: Refer to figures
PSMB3 antibody was tube-contained.
PSMB3 antibody was purified using affinity purification.
Store at -20 Celsius degree. Avoid freeze / thaw cycles.
|Database links|| |
|Protein function|| |
The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
|Protein sequence and domain|| |
Belongs to the peptidase T1B family.
|Protein cellular localization|| |
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. The 26 S proteasome may be involved in trinucleotide repeat expansion, a phenomenon which is associated with many hereditary neurological diseases. Pseudogenes have been identified on chromosomes 2 and 12. Alternative splicing results in multiple transcript variants [provided by RefSeq, Sep 2013]
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|Product type|| |
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