Rabbit polyclonal PSMB5 antibody (A1975)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC,IF
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal PSMB5 antibody (A1975)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC,IF

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200 IF 1:50 – 1:200

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit polyclonal PSMB5 antibody.

Alternative names:

Check alternative names for the antibody

Expand

X antibody, MB1 antibody, LMPX antibody
DKFZp459C139 antibody|EC 3.4.25.1 antibody|LMPX antibody|Macropain epsilon chain antibody|MB1 antibody|MGC104214 antibody|MGC118075 antibody|MGC134464 antibody|Multicatalytic endopeptidase complex epsilon chain antibody|Proteasome (prosome, macropain) subunit, beta type, 5 antibody|Proteasome beta 5 subunit antibody|Proteasome catalytic subunit 3 antibody|Proteasome chain 6 antibody|Proteasome epsilon chain antibody|Proteasome subunit beta type-5 antibody|Proteasome subunit MB1 antibody|Proteasome subunit X antibody|Proteasome subunit, beta type, 5 antibody|Proteasome subunit, beta-5 antibody|PSB5_HUMAN antibody|PSMB5 antibody|PSX large multifunctional protease X antibody|X antibody|Anti-PSMB5 antibody (ab3330)

SCBT cat No: sc-393931|sc-55009|sc-55010|sc-55012|

Name

Rabbit polyclonal PSMB5 antibody

Catalogue No.

A1975

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human PSMB5

Host

Rabbit

Applications

WB, IHC, IF

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200
IF 1:50 – 1:200

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 28kDa/Observed: Refer to Figures

Formulation

PSMB5 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

PSMB5 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

X antibody, MB1 antibody, LMPX antibody

Database links

Human UniProt/Swiss-Prot:P28074

Protein names

X, MB1, LMPX

Protein function

The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. This unit is responsible of the chymotrypsin-like activity of the proteasome and is one of the principal target of the proteasome inhibitor bortezomib. May catalyze basal processing of intracellular antigens. Plays a role in the protection against oxidative damage through the Nrf2-ARE pathway (By similarity).

Protein sequence and domain

Belongs to the peptidase T1B family.

Protein cellular localization

Cytoplasm. Nucleus.

Background

The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit in the proteasome. This catalytic subunit is not present in the immunoproteasome and is replaced by catalytic subunit 3i (proteasome beta 8 subunit). Multiple transcript variants encoding different isoforms have been found for this gene.

Note

AntibodyPlus can customize PSMB5 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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