Rabbit polyclonal PSMC2 antibody (A1985)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC,IF
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal PSMC2 antibody (A1985)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC,IF

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200 IF 1:50 – 1:200

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit polyclonal PSMC2 antibody.

Alternative names:

Check alternative names for the antibody

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S7 antibody, MSS1 antibody, Nbla10058 antibody
26S protease complex antibody|26S protease regulatory subunit 7 antibody|26S proteasome AAA-ATPase subunit RPT1 antibody|mammalian suppressor of sgv-1 of yeast antibody|MSS1 antibody|Nbla10058 antibody|protease 26S subunit 7 antibody|proteasome 26S ATPase subunit 2 antibody|Proteasome 26S subunit ATPase 2 antibody|Proteasome 26S subunit ATPase 2 antibody|Protein MSS1 antibody|PRS7_HUMAN antibody|PSMC2 antibody|putative protein product of Nbla10058 antibody|S7 antibody|Anti-Proteasome 19S S7 antibody (ab3322)

SCBT cat No: sc-166972|sc-98691|

Name

Rabbit polyclonal PSMC2 antibody

Catalogue No.

A1985

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human PSMC2

Host

Rabbit

Applications

WB, IHC, IF

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200
IF 1:50 – 1:200

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 48kDa/Observed: Refer to Figures

Formulation

PSMC2 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

PSMC2 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

S7 antibody, MSS1 antibody, Nbla10058 antibody

Database links

Human UniProt/Swiss-Prot:P35998

Protein names

S7, MSS1, Nbla10058

Protein function

The 26S protease is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex. In case of HIV-1 infection, positive modulator of Tat-mediated transactivation.

Protein sequence and domain

Belongs to the AAA ATPase family.

Protein cellular localization

Cytoplasm. Nucleus. Cytoplasm, P-body . Note: Colocalizes with TRIM5 in the cytoplasmic bodies.

Background

The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases which have a chaperone-like activity. This subunit has been shown to interact with several of the basal transcription factors so, in addition to participation in proteasome functions, this subunit may participate in the regulation of transcription. This subunit may also compete with PSMC3 for binding to the HIV tat protein to regulate the interaction between the viral protein and the transcription complex. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Research area

All research areas>Synthesis and Degradation>PSMC
(View all antibody categories related to Synthesis and Degradation)

Note

AntibodyPlus can customize PSMC2 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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