Rabbit polyclonal PSMC3 antibody (A1986)


Reactivity: Human,Mouse,Rat
Applications: WB,IHC,IF
Conjugation: Unconjugated
Supplier: ABclonal Inc.

-$50 as credit for submitting review for primary antibody
Shipping notice:
Product will be delivered in 6 to 8 Business Days

Rabbit polyclonal PSMC3 antibody (A1986)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC,IF

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200 IF 1:50 – 1:200

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit polyclonal PSMC3 antibody.

Alternative names:

Check alternative names for the antibody


TBP1 antibody
26S protease regulatory subunit 6A antibody|26S proteasome AAA-ATPase subunit RPT5 antibody|Human immunodeficiency virus tat transactivator binding protein 1 antibody|MGC8487 antibody|Proteasome (prosome macropain) 26S subunit ATPase 3 antibody|Proteasome 26S ATPase subunit 3 antibody|Proteasome 26S subunit ATPase 3 antibody|Proteasome subunit P50 antibody|PRS6A_HUMAN antibody|PSMC 3 antibody|PSMC3 antibody|Tat binding protein 1 antibody|TAT-binding protein 1 antibody|TBP-1 antibody|TBP1 antibody|Anti-PSMC3 antibody [EPR12152] – N-terminal (ab171969)

SCBT cat No: sc-100462|


Rabbit polyclonal PSMC3 antibody

Catalogue No.



Human, Mouse, Rat


Recombinant protein of human PSMC3





Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200
IF 1:50 – 1:200







Molecular weight

Predicted: 49kDa/Observed: Refer to Figures


PSMC3 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.


PSMC3 antibody was purified using affinity purification.


Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

TBP1 antibody

Database links

Human UniProt/Swiss-Prot:P17980

Protein names


Protein function

The 26S protease is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex (By similarity). In case of HIV-1 infection, suppresses Tat-mediated transactivation.

Protein sequence and domain

Belongs to the AAA ATPase family.

Protein post-translational modifications

Sumoylated by UBE2I in response to MEKK1-mediated stimuli.

Protein cellular localization

Cytoplasm . Nucleus . Cytoplasm, P-body . Note: Colocalizes with TRIM5 in the cytoplasmic bodies.


The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases that have chaperone-like activity. This subunit may compete with PSMC2 for binding to the HIV tat protein to regulate the interaction between the viral protein and the transcription complex. A pseudogene has been identified on chromosome 9.

Research area

All research areas>Synthesis and Degradation>PSMC
(View all antibody categories related to Synthesis and Degradation)


AntibodyPlus can customize PSMC3 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody


ABclonal Inc.


There are no reviews yet.

Only logged in customers who have purchased this product may leave a review

There are no reviews for this product yet.
By submitting a review, get following benefits:

1. Receive $50 ABcoins as credit for each review.
2. First trial sample order will be fully refunded as credit.
3. Have a chance to win a $50 amazon gift card!

view database submit reviews

There is no extra validation for this product yet.
Check other extra validated antibodies below:

Welcome to AntibodyPlus!