Rabbit polyclonal PSMD2 antibody (A1999)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC,IF
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal PSMD2 antibody (A1999)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC,IF

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200 IF 1:50 – 1:200

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit polyclonal PSMD2 antibody.

Alternative names:

Check alternative names for the antibody

Expand

S2 antibody, P97 antibody, RPN1 antibody, TRAP2 antibody
26S proteasome non-ATPase regulatory subunit 2 antibody|26S proteasome regulatory subunit RPN1 antibody|26S proteasome regulatory subunit S2 antibody|26S proteasome subunit p97 antibody|55.11 protein antibody|MGC14274 antibody|P97 antibody|Proteasome (prosome macropain) 26S subunit non ATPase 2 antibody|Proteasome 26S subunit, non-ATPase, 2 antibody|Proteasome 26S, subunit 2 antibody|Protein 55.11 antibody|Psmd2 antibody|PSMD2_HUMAN antibody|Rpn1 antibody|S2 antibody|TNFR associated protein 2 antibody|TRAP2 antibody|Tumor necrosis factor receptor associated protein 2 antibody|Tumor necrosis factor type 1 receptor-associated protein 2 antibody|Anti-Proteasome 26S S2 antibody (ab140675)

SCBT cat No: sc-271775|sc-271584|

Name

Rabbit polyclonal PSMD2 antibody

Catalogue No.

A1999

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human PSMD2

Host

Rabbit

Applications

WB, IHC, IF

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200
IF 1:50 – 1:200

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 100kDa/Observed: Refer to Figures

Formulation

PSMD2 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

PSMD2 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

S2 antibody, P97 antibody, RPN1 antibody, TRAP2 antibody

Database links

Human UniProt/Swiss-Prot:Q13200

Protein names

S2, P97, RPN1, TRAP2

Protein function

Acts as a regulatory subunit of the 26 proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.; Binds to the intracellular domain of tumor necrosis factor type 1 receptor. The binding domain of TRAP1 and TRAP2 resides outside the death domain of TNFR1.

Protein tissue specificity

Found in skeletal muscle, liver, heart, brain, kidney, pancreas, lung and placenta.

Protein sequence and domain

Belongs to the proteasome subunit S2 family.; Contains 7 PC repeats.

Background

The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the non-ATPase subunits of the 19S regulator lid. In addition to participation in proteasome function, this subunit may also participate in the TNF signalling pathway since it interacts with the tumor necrosis factor type 1 receptor. A pseudogene has been identified on chromosome 1. Alternative splicing results in multiple transcript variants of this gene.

Research area

All research areas>Synthesis and Degradation>PSMD
(View all antibody categories related to Synthesis and Degradation)

Note

AntibodyPlus can customize PSMD2 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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