Rabbit Polyclonal PSMD4 antibody (A1061)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit Polyclonal PSMD4 antibody (A1061)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC

Recommended dilution:

WB 1:500 – 1:2000
IHC 1:50 – 1:200

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit Polyclonal PSMD4 antibody.

Alternative names:

Check alternative names for the antibody

Expand

PSMD4 antibody;AF antibody;AF-1 antibody;ASF antibody;MCB1 antibody;Rpn10 antibody;S5A antibody;pUB-R5 antibody;
26S protease subunit S5a antibody|26S proteasome non ATPase regulatory subunit 4 antibody|26S proteasome non-ATPase regulatory subunit 4 antibody|26S proteasome regulatory subunit rpn10 antibody|26S proteasome regulatory subunit S5A antibody|AF 1 antibody|AF antibody|AF1 antibody|Angiocidin antibody|Antisecretory factor 1 antibody|ASF antibody|DS5a antibody|MCB 1 antibody|MCB1 antibody|Multiubiquitin chain binding protein antibody|Multiubiquitin chain-binding protein antibody|OTTHUMP00000059963 antibody|Prosome macropain antibody|Proteasome (prosome macropain) 26S subunit non ATPase 4 antibody|Proteasome 26S non ATPase subunit 4 antibody|Proteasome 26S subunit non ATPase 4 antibody|PSMD 4 antibody|Psmd4 antibody|PSMD4_HUMAN antibody|pUB R5 antibody|pUBR5 antibody|Rpn 10 antibody|Rpn10 antibody|RPN10 homolog antibody|S5A antibody|S5a/antisecretory factor protein antibody|Anti-Proteasome 19S S5A antibody [AH1.1] (ab20239)

SCBT cat No: sc-53425|sc-393546|sc-398033|sc-100461|

Name

Rabbit Polyclonal PSMD4 antibody

Catalogue No.

A1061

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human PSMD4

Host

Rabbit

Applications

WB, IHC

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

41kDa

Formulation

PSMD4 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

Affinity purification

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

PSMD4 antibody;AF antibody;AF-1 antibody;ASF antibody;MCB1 antibody;Rpn10 antibody;S5A antibody;pUB-R5 antibody;

Database links

Human UniProt/Swiss-Prot:P55036

Protein names

PSMD4;AF;AF-1;ASF;MCB1;Rpn10;S5A;pUB-R5 ;

Protein function

Binds and presumably selects ubiquitin-conjugates for destruction. Displays selectivity for longer polyubiquitin chains. Modulates intestinal fluid secretion.

Protein sequence and domain

Belongs to the proteasome subunit S5A family.; Contains 2 UIM (ubiquitin-interacting motif) domains.; Contains 1 VWFA domain. The 2 UIM motifs are involved in the binding to a multi-ubiquitin chain in a cooperative way.

Background

S5a (PSMD4) is a subunit of the 19S regulatory proteasome complex functioning in ubiquitinated-protein targeting and degradation (1). S5a contains two polyubiquitin binding motifs (UIM) that bind multiubiquitin chains by hydrophobic interaction (2,3). In addition to ubiquitin, the UIM of S5a shows high affinity to a ubiquitin-like domain present in many proteins. S5a binds to these types of proteins directly and mediates their targeting to the proteasome for degradation (4,5).

Note

AntibodyPlus can customize PSMD4 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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