Rabbit polyclonal PSME1 antibody (A5358)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC,IF
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal PSME1 antibody (A5358)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC,IF

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200 IF 1:50 – 1:200

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit polyclonal PSME1 antibody.

Alternative names:

Check alternative names for the antibody

Expand

PA28A antibody, IFI5111 antibody, REGalpha antibody, PA28alpha antibody
11S regulator complex alpha subunit antibody|11S regulator complex subunit alpha antibody|29 kD MCP activator subunit antibody|29kD MCP activator subunit antibody|Activator of multicatalytic protease subunit 1 antibody|IFI5111 antibody|IGUP I-5111 antibody|Interferon gamma IEF SSP 5111 antibody|Interferon gamma inducible protein 5111 antibody|Interferon gamma up regulated I 5111 protein antibody|Interferon gamma up-regulated I-5111 protein antibody|MGC8628 antibody|PA28a antibody|PA28alpha antibody|Proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) antibody|Proteasome activator 28 subunit alpha antibody|Proteasome activator complex subunit 1 antibody|Proteasome activator subunit 1 antibody|PSME1 antibody|PSME1_HUMAN antibody|REG-alpha antibody|REGalpha antibody|Anti-PSME1 antibody (ab186832)

SCBT cat No: sc-21267|

Name

Rabbit polyclonal PSME1 antibody

Catalogue No.

A5358

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human PSME1

Host

Rabbit

Applications

WB, IHC, IF

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200
IF 1:50 – 1:200

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 28kDa/Observed: Refer to Figures

Formulation

PSME1 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

PSME1 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

PA28A antibody, IFI5111 antibody, REGalpha antibody, PA28alpha antibody

Database links

Human UniProt/Swiss-Prot:Q06323

Protein names

PA28A, IFI5111, REGalpha, PA28alpha

Protein function

Implicated in immunoproteasome assembly and required for efficient antigen processing. The PA28 activator complex enhances the generation of class I binding peptides by altering the cleavage pattern of the proteasome.

Protein sequence and domain

Belongs to the PA28 family.

Background

The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. The immunoproteasome contains an alternate regulator, referred to as the 11S regulator or PA28, that replaces the 19S regulator. Three subunits (alpha, beta and gamma) of the 11S regulator have been identified. This gene encodes the alpha subunit of the 11S regulator, one of the two 11S subunits that is induced by gamma-interferon. Three alpha and three beta subunits combine to form a heterohexameric ring. Alternative splicing results in multiple transcript variants.

Research area

All research areas>Signaling Intermediates>PA28
(View all antibody categories related to Signaling Intermediates)

Note

AntibodyPlus can customize PSME1 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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