Rabbit polyclonal PSME2 antibody (A5562)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal PSME2 antibody (A5562)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit polyclonal PSME2 antibody.

Alternative names:

Check alternative names for the antibody

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PA28B antibody, REGbeta antibody, PA28beta antibody
11S regulator complex beta subunit antibody|11S regulator complex subunit beta antibody|Activator of multicatalytic protease subunit 2 antibody|Cell migration inducing protein 22 antibody|MCP activator 31 kD subunit antibody|PA28 beta antibody|PA28b antibody|PA28beta antibody|Proteasome (prosome macropain) activator subunit 2 (PA28 beta) antibody|Proteasome (prosome macropain) activator subunit 2 antibody|Proteasome activator 28 beta antibody|Proteasome activator 28 subunit beta antibody|Proteasome activator complex subunit 2 antibody|Proteasome activator hPA28 subunit beta antibody|Proteasome activator subunit 2 antibody|PSME 2 antibody|PSME2 antibody|PSME2_HUMAN antibody|REG beta antibody|REG-beta antibody|REGbeta antibody|Anti-PSME2 antibody [EPR14931] (ab183727)

SCBT cat No: sc-100799|sc-390563|sc-292774|sc-23642|sc-21270|

Name

Rabbit polyclonal PSME2 antibody

Catalogue No.

A5562

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human PSME2

Host

Rabbit

Applications

WB, IHC

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 27kDa/Observed: Refer to Figures

Formulation

PSME2 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

PSME2 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

PA28B antibody, REGbeta antibody, PA28beta antibody

Database links

Human UniProt/Swiss-Prot:Q9UL46

Protein names

PA28B, REGbeta, PA28beta

Protein function

Implicated in immunoproteasome assembly and required for efficient antigen processing. The PA28 activator complex enhances the generation of class I binding peptides by altering the cleavage pattern of the proteasome.

Protein sequence and domain

Belongs to the PA28 family.

Background

The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. The immunoproteasome contains an alternate regulator, referred to as the 11S regulator or PA28, that replaces the 19S regulator. Three subunits (alpha, beta and gamma) of the 11S regulator have been identified. This gene encodes the beta subunit of the 11S regulator, one of the two 11S subunits that is induced by gamma-interferon. Three beta and three alpha subunits combine to form a heterohexameric ring. Six pseudogenes have been identified on chromosomes 4, 5, 8, 10 and 13.

Research area

All research areas>Signaling Intermediates>PA28
(View all antibody categories related to Signaling Intermediates)

Note

AntibodyPlus can customize PSME2 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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