Rabbit polyclonal PSMF1 antibody (A5554)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal PSMF1 antibody (A5554)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

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PI31 antibody
hPI31 antibody|PI31 antibody|Proteasome (prosome macropain) inhibitor subunit 1 antibody|Proteasome inhibitor hP131 subunit antibody|Proteasome inhibitor PI31 subunit antibody|PSMB2 antibody|Psmf1 antibody|PSMF1_HUMAN antibody|RP23 402M7.5 antibody|RP4 545L17.1 antibody|Anti-Proteasome Inhibitor subunit 1 PI3 1 antibody (ab140497)

SCBT cat No: sc-136416|

Name

Rabbit polyclonal PSMF1 antibody

Catalogue No.

A5554

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human PSMF1

Host

Rabbit

Applications

WB, IHC

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 29kDa/Observed: Refer to Figures

Formulation

PSMF1 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

PSMF1 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

PI31 antibody

Database links

Human UniProt/Swiss-Prot:Q92530

Protein names

PI31

Protein function

Plays an important role in control of proteasome function. Inhibits the hydrolysis of protein and peptide substrates by the 20S proteasome. Also inhibits the activation of the proteasome by the proteasome regulatory proteins PA700 and PA28.

Protein sequence and domain

Belongs to the proteasome inhibitor PI31 family.

Protein cellular localization

Cytoplasm . Endoplasmic reticulum .

Background

The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a protein that inhibits the activation of the proteasome by the 11S and 19S regulators. Alternative transcript variants have been identified for this gene.

Note

AntibodyPlus can customize PSMF1 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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