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Rabbit polyclonal PSMF1 antibody (A5554)
Supplier: ABclonal Inc.
Recommended applications: WB,IHC
WB 1:500 – 1:2000 IHC 1:50 – 1:200
Recommended protocols: check protocols
Click or hover above images to see image description for Rabbit polyclonal PSMF1 antibody.
Check alternative names for the antibodyExpand
hPI31 antibody|PI31 antibody|Proteasome (prosome macropain) inhibitor subunit 1 antibody|Proteasome inhibitor hP131 subunit antibody|Proteasome inhibitor PI31 subunit antibody|PSMB2 antibody|Psmf1 antibody|PSMF1_HUMAN antibody|RP23 402M7.5 antibody|RP4 545L17.1 antibody|Anti-Proteasome Inhibitor subunit 1 PI3 1 antibody (ab140497)
SCBT cat No: sc-136416|
Rabbit polyclonal PSMF1 antibody
|Catalogue No.|| |
Human, Mouse, Rat
Recombinant protein of human PSMF1
|Recommended dilution|| |
WB 1:500 – 1:2000
|Molecular weight|| |
Predicted: 29kDa/Observed: Refer to Figures
PSMF1 antibody was tube-contained.
PSMF1 antibody was purified using affinity purification.
Store at -20 Celsius degree. Avoid freeze / thaw cycles.
|Alternative antibody names|| |
|Database links|| |
|Protein names|| |
|Protein function|| |
Plays an important role in control of proteasome function. Inhibits the hydrolysis of protein and peptide substrates by the 20S proteasome. Also inhibits the activation of the proteasome by the proteasome regulatory proteins PA700 and PA28.
|Protein sequence and domain|| |
Belongs to the proteasome inhibitor PI31 family.
|Protein cellular localization|| |
Cytoplasm . Endoplasmic reticulum .
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a protein that inhibits the activation of the proteasome by the 11S and 19S regulators. Alternative transcript variants have been identified for this gene.
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|Product type|| |
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