Rabbit polyclonal PTBP2 antibody (A6054)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal PTBP2 antibody (A6054)

Supplier: ABclonal Inc.

Recommended applications: WB

Recommended dilution:

WB 1:1000 – 1:4000

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit polyclonal PTBP2 antibody.

Alternative names:

Check alternative names for the antibody

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PTB antibody, nPTB antibody, PTBLP antibody, brPTB antibody, nPTB5 antibody, nPTB6 antibody, nPTB7 antibody, nPTB8 antibody
brPTB antibody|FLJ34897 antibody|MIBP antibody|Neural polypyrimidine tract binding protein antibody|Neural polypyrimidine tract-binding protein antibody|Neurally enriched homolog of PTB antibody|Neurally-enriched homolog of PTB antibody|nPTB 5 antibody|nPTB 6 antibody|nPTB 7 antibody|nPTB 8 antibody|nPTB antibody|nPTB5 antibody|nPTB6 antibody|nPTB7 antibody|nPTB8 antibody|Polypyrimidine tract binding protein 2 antibody|Polypyrimidine tract-binding protein 2 antibody|PTB antibody|PTB like antibody|PTB like protein antibody|PTB-like protein antibody|PTBLP antibody|PTBP 2 antibody|Ptbp2 antibody|PTBP2_HUMAN antibody|Splicing regulator antibody|Anti-PTBP2 antibody [EPR9890] (ab154787)

SCBT cat No: sc-376316|sc-98491|sc-103847|sc-101183|

Name

Rabbit polyclonal PTBP2 antibody

Catalogue No.

A6054

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human PTBP2

Host

Rabbit

Applications

WB

Recommended dilution

WB 1:1000 – 1:4000

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 57kDa/Observed: Refer to Figures

Formulation

PTBP2 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

PTBP2 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

PTB antibody, nPTB antibody, PTBLP antibody, brPTB antibody, nPTB5 antibody, nPTB6 antibody, nPTB7 antibody, nPTB8 antibody

Database links

Human UniProt/Swiss-Prot:Q9UKA9

Protein names

PTB, nPTB, PTBLP, brPTB, nPTB5, nPTB6, nPTB7, nPTB8

Protein function

RNA-binding protein which binds to intronic polypyrimidine tracts and mediates negative regulation of exons splicing. May antagonize in a tissue-specific manner the ability of NOVA1 to activate exon selection. In addition to its function in pre-mRNA splicing, plays also a role in the regulation of translation. Isoform 5 has a reduced affinity for RNA.

Protein tissue specificity

Mainly expressed in brain although also detected in other tissues like heart and skeletal muscle. Isoform 1 and isoform 2 are specifically expressed in neuronal tissues. Isoform 3 and isoform 4 are expressed in non-neuronal tissues. Isoform 5 and isoform 6 are truncated forms expressed in non-neuronal tissues.

Protein sequence and domain

Contains 4 RRM (RNA recognition motif) domains.

Protein cellular localization

Nucleus .

Background

The protein encoded by this gene binds to the intronic cluster of RNA regulatory elements, downstream control sequence (DCS). It is implicated in controlling the assembly of other splicing-regulatory proteins. This protein is very similar to the polypyrimidine tract binding protein but it is expressed primarily in the brain.

Note

AntibodyPlus can customize PTBP2 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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