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Rabbit polyclonal PTK7 antibody (A9839)
Supplier: ABclonal Inc.
Recommended applications: WB,IHC
WB 1:500 – 1:2000 IHC 1:50 – 1:100
Recommended protocols: check protocols
Click or hover above images to see image description for Rabbit polyclonal PTK7 antibody.
Check alternative names for the antibodyExpand
8430404F20Rik antibody|CCK 4 antibody|CCK-4 antibody|Colon carcinoma kinase 4 antibody|Human colon carcinoma kinase 4 (CCK4) mRNA complete cds antibody|Inactive tyrosine-protein kinase 7 antibody|mPTK7/CCK4 antibody|OTTHUMP00000217016 antibody|Protein tyrosine kinase PTK 7 antibody|Protein-tyrosine kinase 7 antibody|Pseudo tyrosine kinase receptor 7 antibody|PTK 7 antibody|PTK7 antibody|PTK7 protein tyrosine kinase 7 antibody|PTK7 protein tyrosine kinase antibody|PTK7_HUMAN antibody|Serum response factor antibody|Srf antibody|Tyrosine-protein kinase-like 7 antibody|Anti-CCK4 antibody (ab117412)
SCBT cat No: sc-100304|
Rabbit polyclonal PTK7 antibody
|Catalogue No.|| |
Human, Mouse, Rat
Recombinant protein of human PTK7
|Recommended dilution|| |
WB 1:500 – 1:2000
|Molecular weight|| |
Predicted: 118kDa/Observed: Refer to figures
PTK7 antibody was tube-contained.
PTK7 antibody was purified using affinity purification.
Store at -20 Celsius degree. Avoid freeze / thaw cycles.
|Database links|| |
|Protein function|| |
Inactive tyrosine kinase involved in Wnt signaling pathway. Component of both the non-canonical (also known as the Wnt/planar cell polarity signaling) and the canonical Wnt signaling pathway. Functions in cell adhesion, cell migration, cell polarity, proliferation, actin cytoskeleton reorganization and apoptosis. Has a role in embryogenesis, epithelial tissue organization and angiogenesis.
|Protein tissue specificity|| |
Highly expressed in lung, liver, pancreas, kidney, placenta and melanocytes. Weakly expressed in thyroid gland, ovary, brain, heart and skeletal muscle. Also expressed in erythroleukemia cells. But not expressed in colon.
|Protein sequence and domain|| |
The protein kinase domain is predicted to be catalytically inactive.Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.; Contains 7 Ig-like C2-type (immunoglobulin-like) domains.; Contains 1 protein kinase domain.
|Protein post-translational modifications|| |
MMP14 cleaves PTK7 between Pro-621 and Leu-622 generating an N-terminal soluble (70 kDa) fragment and a membrane C-terminal (50 kDa) fragment. Proteolysis by MMP14 regulates PTK7 function in non-canonical Wnt signaling pathway.
|Protein cellular localization|| |
Membrane ; Single-pass type I membrane protein . Cell junction . Note: Colocalizes with MMP14 at cell junctions. Also localizes at the leading edge of migrating cells.
AntibodyPlus can customize PTK7 antibody according to your requirement, including bulk product size,etc. Please contact firstname.lastname@example.org. AntibodyPlus provides antibody trial sample for your own antibody validation.
|Product type|| |
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