Rabbit polyclonal RAB31 antibody (A7506)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC,IF
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal RAB31 antibody (A7506)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC,IF

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200 IF 1:50 – 1:200

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

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Rab22B antibody
Rab 22B antibody||Anti-RAB31 antibody (ab89163)

SCBT cat No: sc-517069|sc-85111|sc-85113|

Name

Rabbit polyclonal RAB31 antibody

Catalogue No.

A7506

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human RAB31

Host

Rabbit

Applications

WB, IHC, IF

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200
IF 1:50 – 1:200

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 22kDa/Observed: Refer to figures

Formulation

RAB31 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

RAB31 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

Rab22B antibody

Database links

Human UniProt/Swiss-Prot:Q13636

Protein names

Rab22B

Protein function

The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. Required for the integrity and for normal function of the Golgi apparatus and the trans-Golgi network. Plays a role in insulin-stimulated translocation of GLUT4 to the cell membrane. Plays a role in M6PR transport from the trans-Golgi network to endosomes. Plays a role in the internalization of EGFR from the cell membrane into endosomes. Plays a role in the maturation of phagosomes that engulf pathogens, such as S.aureus and M.tuberculosis.

Protein tissue specificity

Highest expression in placenta and brain with lower levels in heart and lung. Not detected in liver, skeletal muscle, kidney or pancreas.

Protein sequence and domain

Belongs to the small GTPase superfamily. Rab family.

Protein cellular localization

Golgi apparatus, trans-Golgi network . Golgi apparatus, trans-Golgi network membrane ; Lipid-anchor ; Cytoplasmic side . Early endosome . Cytoplasmic vesicle, phagosome . Cytoplasmic vesicle, phagosome membrane ; Lipid-anchor ; Cytoplasmic side . Note: Rapidly recruited to phagosomes containing S.aureus or M.tuberculosis .

Background

Small GTP-binding proteins of the RAB family, such as RAB31, play essential roles in vesicle and granule targeting (Bao et al., 2002

Research area

All research areas>GDP/GTP Binding Proteins>Rab
(View all antibody categories related to GDP/GTP Binding Proteins)

Note

AntibodyPlus can customize RAB31 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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