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Rabbit polyclonal RAB31 antibody (A7506)
Supplier: ABclonal Inc.
Recommended applications: WB,IHC,IF
WB 1:500 – 1:2000 IHC 1:50 – 1:200 IF 1:50 – 1:200
Recommended protocols: check protocols
Click or hover above images to see image description for Rabbit polyclonal RAB31 antibody.
Check alternative names for the antibodyExpand
Rab 22B antibody||Anti-RAB31 antibody (ab89163)
SCBT cat No: sc-517069|sc-85111|sc-85113|
Rabbit polyclonal RAB31 antibody
|Catalogue No.|| |
Human, Mouse, Rat
Recombinant protein of human RAB31
WB, IHC, IF
|Recommended dilution|| |
WB 1:500 – 1:2000
|Molecular weight|| |
Predicted: 22kDa/Observed: Refer to figures
RAB31 antibody was tube-contained.
RAB31 antibody was purified using affinity purification.
Store at -20 Celsius degree. Avoid freeze / thaw cycles.
|Alternative antibody names|| |
|Database links|| |
|Protein names|| |
|Protein function|| |
The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. Required for the integrity and for normal function of the Golgi apparatus and the trans-Golgi network. Plays a role in insulin-stimulated translocation of GLUT4 to the cell membrane. Plays a role in M6PR transport from the trans-Golgi network to endosomes. Plays a role in the internalization of EGFR from the cell membrane into endosomes. Plays a role in the maturation of phagosomes that engulf pathogens, such as S.aureus and M.tuberculosis.
|Protein tissue specificity|| |
Highest expression in placenta and brain with lower levels in heart and lung. Not detected in liver, skeletal muscle, kidney or pancreas.
|Protein sequence and domain|| |
Belongs to the small GTPase superfamily. Rab family.
|Protein cellular localization|| |
Golgi apparatus, trans-Golgi network . Golgi apparatus, trans-Golgi network membrane ; Lipid-anchor ; Cytoplasmic side . Early endosome . Cytoplasmic vesicle, phagosome . Cytoplasmic vesicle, phagosome membrane ; Lipid-anchor ; Cytoplasmic side . Note: Rapidly recruited to phagosomes containing S.aureus or M.tuberculosis .
Small GTP-binding proteins of the RAB family, such as RAB31, play essential roles in vesicle and granule targeting (Bao et al., 2002
AntibodyPlus can customize RAB31 antibody according to your requirement, including bulk product size,etc. Please contact firstname.lastname@example.org. AntibodyPlus provides antibody trial sample for your own antibody validation.
|Product type|| |
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