Rabbit polyclonal RAB3IP antibody (A8094)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal RAB3IP antibody (A8094)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit polyclonal RAB3IP antibody.

Alternative names:

Check alternative names for the antibody

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RABIN3 antibody, RABIN8 antibody
Gtpat12 antibody|Rab-3A-interacting protein antibody|RAB3A interacting protein antibody|RAB3A interacting protein (rabin3) antibody|RAB3A interacting protein antibody|RAB3A-interacting protein antibody|RAB3I_HUMAN antibody|Rab3ip antibody|Rabin 3 antibody|Rabin-3 antibody|RABIN3 antibody|RABIN3, rat, homolog of antibody|Rabin8 antibody|SSX2 interacting protein antibody|SSX2 interacting protein antibody|SSX2-interacting protein antibody|Anti-RAB3IP antibody (ab90732)

SCBT cat No: sc-162067|

Name

Rabbit polyclonal RAB3IP antibody

Catalogue No.

A8094

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human RAB3IP

Host

Rabbit

Applications

WB, IHC

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 53kDa/Observed: Refer to Figures

Formulation

RAB3IP antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

RAB3IP antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

RABIN3 antibody, RABIN8 antibody

Database links

Human UniProt/Swiss-Prot:Q96QF0

Protein names

RABIN3, RABIN8

Protein function

Guanine nucleotide exchange factor (GEF) which may activate RAB8A and RAB8B. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form. Mediates the release of GDP from RAB8A and RAB8B but not from RAB3A or RAB5. Modulates actin organization and promotes polarized transport of RAB8A-specific vesicles to the cell surface. Together with RAB11A, RAB8A, the exocyst complex, PARD3, PRKCI, ANXA2, CDC42 and DNMBP promotes transcytosis of PODXL to the apical membrane initiation sites (AMIS), apical surface formation and lumenogenesis.

Protein tissue specificity

Expressed in brain, kidney, heart, pancreas and placenta. Not detected in skeletal muscle or liver.

Protein sequence and domain

Belongs to the SEC2 family.

Protein cellular localization

Cytoplasm. Nucleus. Cytoplasm, cytoskeleton. Cell projection, lamellipodium. Note: Predominantly cytoplasmic but a small proportion colocalizes with SSX2 in the nucleus. Activation of protein kinase C results in redistribution to the periphery of lamellipodia. In the cytoskeleton, localizes to cortical actin.

Background

RAB3IP (RAB3A interacting protein) is a protein-coding gene. GO annotations related to this gene include Rab guanyl-nucleotide exchange factor activity. An important paralog of this gene is RAB3IL1.

Research area

All research areas>GDP/GTP Binding Proteins>RAB3IP
(View all antibody categories related to GDP/GTP Binding Proteins)

Note

AntibodyPlus can customize RAB3IP antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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