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Rabbit polyclonal RAB3IP antibody (A8094)
Supplier: ABclonal Inc.
Recommended applications: WB,IHC
WB 1:500 – 1:2000 IHC 1:50 – 1:200
Recommended protocols: check protocols
Click or hover above images to see image description for Rabbit polyclonal RAB3IP antibody.
Check alternative names for the antibodyExpand
RABIN3 antibody, RABIN8 antibody
Gtpat12 antibody|Rab-3A-interacting protein antibody|RAB3A interacting protein antibody|RAB3A interacting protein (rabin3) antibody|RAB3A interacting protein antibody|RAB3A-interacting protein antibody|RAB3I_HUMAN antibody|Rab3ip antibody|Rabin 3 antibody|Rabin-3 antibody|RABIN3 antibody|RABIN3, rat, homolog of antibody|Rabin8 antibody|SSX2 interacting protein antibody|SSX2 interacting protein antibody|SSX2-interacting protein antibody|Anti-RAB3IP antibody (ab90732)
SCBT cat No: sc-162067|
Rabbit polyclonal RAB3IP antibody
|Catalogue No.|| |
Human, Mouse, Rat
Recombinant protein of human RAB3IP
|Recommended dilution|| |
WB 1:500 – 1:2000
|Molecular weight|| |
Predicted: 53kDa/Observed: Refer to Figures
RAB3IP antibody was tube-contained.
RAB3IP antibody was purified using affinity purification.
Store at -20 Celsius degree. Avoid freeze / thaw cycles.
|Alternative antibody names|| |
RABIN3 antibody, RABIN8 antibody
|Database links|| |
|Protein names|| |
|Protein function|| |
Guanine nucleotide exchange factor (GEF) which may activate RAB8A and RAB8B. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form. Mediates the release of GDP from RAB8A and RAB8B but not from RAB3A or RAB5. Modulates actin organization and promotes polarized transport of RAB8A-specific vesicles to the cell surface. Together with RAB11A, RAB8A, the exocyst complex, PARD3, PRKCI, ANXA2, CDC42 and DNMBP promotes transcytosis of PODXL to the apical membrane initiation sites (AMIS), apical surface formation and lumenogenesis.
|Protein tissue specificity|| |
Expressed in brain, kidney, heart, pancreas and placenta. Not detected in skeletal muscle or liver.
|Protein sequence and domain|| |
Belongs to the SEC2 family.
|Protein cellular localization|| |
Cytoplasm. Nucleus. Cytoplasm, cytoskeleton. Cell projection, lamellipodium. Note: Predominantly cytoplasmic but a small proportion colocalizes with SSX2 in the nucleus. Activation of protein kinase C results in redistribution to the periphery of lamellipodia. In the cytoskeleton, localizes to cortical actin.
RAB3IP (RAB3A interacting protein) is a protein-coding gene. GO annotations related to this gene include Rab guanyl-nucleotide exchange factor activity. An important paralog of this gene is RAB3IL1.
AntibodyPlus can customize RAB3IP antibody according to your requirement, including bulk product size,etc. Please contact email@example.com. AntibodyPlus provides antibody trial sample for your own antibody validation.
|Product type|| |
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