Rabbit polyclonal RAMP1 antibody (A6447)

$69.00$259.00

Reactivity: Human
Applications: WB,IHC
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal RAMP1 antibody (A6447)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

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Calcitonin receptor like receptor activity modifying protein 1 antibody|Calcitonin-receptor-like receptor activity-modifying protein 1 antibody|CRLR activity modifying protein 1 antibody|CRLR activity-modifying protein 1 antibody|Ramp1 antibody|RAMP1_HUMAN antibody|receptor (calcitonin) activity modifying protein 1 antibody|Receptor (G protein coupled) activity modifying protein 1 antibody|Receptor activity modifying protein 1 [Precursor] antibody|Receptor activity-modifying protein 1 antibody|Anti-RAMP1 antibody [EPR10867] (ab156575)

SCBT cat No: sc-293438|sc-8851|sc-11379|sc-8850|

Name

Rabbit polyclonal RAMP1 antibody

Catalogue No.

A6447

Reactivity

Human

Immunogen

Recombinant protein of human RAMP1

Host

Rabbit

Applications

WB, IHC

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 16kDa/Observed: Refer to Figures

Formulation

RAMP1 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

RAMP1 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Database links

Human UniProt/Swiss-Prot:O60894

Protein function

Transports the calcitonin gene-related peptide type 1 receptor (CALCRL) to the plasma membrane. Acts as a receptor for calcitonin-gene-related peptide (CGRP) together with CALCRL.

Protein tissue specificity

Expressed in many tissues including the uterus, bladder, brain, pancreas and gastro-intestinal tract.

Protein sequence and domain

Belongs to the RAMP family.

Protein cellular localization

Membrane; Single-pass type I membrane protein.

Background

The protein encoded by this gene is a member of the RAMP family of single-transmembrane-domain proteins, called receptor (calcitonin) activity modifying proteins (RAMPs). RAMPs are type I transmembrane proteins with an extracellular N terminus and a cytoplasmic C terminus. RAMPs are required to transport calcitonin-receptor-like receptor (CRLR) to the plasma membrane. CRLR, a receptor with seven transmembrane domains, can function as either a calcitonin-gene-related peptide (CGRP) receptor or an adrenomedullin receptor, depending on which members of the RAMP family are expressed. In the presence of this (RAMP1) protein, CRLR functions as a CGRP receptor. The RAMP1 protein is involved in the terminal glycosylation, maturation, and presentation of the CGRP receptor to the cell surface.

Note

AntibodyPlus can customize RAMP1 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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