Rabbit polyclonal RBBP7 antibody (A6967)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC,IF
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal RBBP7 antibody (A6967)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC,IF

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200 IF 1:50 – 1:200

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

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RbAp46 antibody
G1/S transition control protein binding protein RbAp46 antibody|Histone acetyltransferase type B subunit 2 antibody|Histone binding protein RBBP7 antibody|Histone-binding protein RBBP7 antibody|MGC138867 antibody|MGC138868 antibody|Nucleosome remodeling factor subunit RBAP46 antibody|Nucleosome-remodeling factor subunit RBAP46 antibody|RBAP46 antibody|RBBP 7 antibody|RBBP-7 antibody|RBBP7 antibody|RBBP7_HUMAN antibody|Retinoblastoma binding protein 7 antibody|Retinoblastoma binding protein p46 antibody|Retinoblastoma-binding protein 7 antibody|Retinoblastoma-binding protein p46 antibody|Retinoblastoma-binding protein RbAp46 antibody|Anti-RbAp46 antibody (ab3535)

SCBT cat No: sc-377197|sc-8272|

Name

Rabbit polyclonal RBBP7 antibody

Catalogue No.

A6967

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human RBBP7

Host

Rabbit

Applications

WB, IHC, IF

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200
IF 1:50 – 1:200

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 48kDa/Observed: Refer to figures

Formulation

RBBP7 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

RBBP7 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

RbAp46 antibody

Database links

Human UniProt/Swiss-Prot:Q16576

Protein names

RbAp46

Protein function

Core histone-binding subunit that may target chromatin remodeling factors, histone acetyltransferases and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA. Component of several complexes which regulate chromatin metabolism. These include the type B histone acetyltransferase (HAT) complex, which is required for chromatin assembly following DNA replication; the core histone deacetylase (HDAC) complex, which promotes histone deacetylation and consequent transcriptional repression; the nucleosome remodeling and histone deacetylase complex (the NuRD complex), which promotes transcriptional repression by histone deacetylation and nucleosome remodeling; and the PRC2/EED-EZH2 complex, which promotes repression of homeotic genes during development; and the NURF (nucleosome remodeling factor) complex.

Protein sequence and domain

Belongs to the WD repeat RBAP46/RBAP48/MSI1 family.; Contains 7 WD repeats.

Protein cellular localization

Nucleus.

Background

This protein is a ubiquitously expressed nuclear protein and belongs to a highly conserved subfamily of WD-repeat proteins. It is found among several proteins that binds directly to retinoblastoma protein, which regulates cell proliferation. The encoded protein is found in many histone deacetylase complexes, including mSin3 co-repressor complex. It is also present in protein complexes involved in chromatin assembly. This protein can interact with BRCA1 tumor-suppressor gene and may have a role in the regulation of cell proliferation and differentiation. Two transcript variants encoding different isoforms have been found for this gene.

Note

AntibodyPlus can customize RBBP7 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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