Rabbit polyclonal RBP3 antibody (A6403)

$69.00$259.00

Reactivity: Human
Applications: WB,IHC,IF
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal RBP3 antibody (A6403)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC,IF

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200 IF 1:50 – 1:100

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

Expand

IRBP antibody, RBPI antibody, RP66 antibody, D10S64 antibody, D10S65 antibody, D10S66 antibody
D10S64 antibody|D10S65 antibody|D10S66 antibody|Interphotoreceptor retinoid binding protein antibody|Interphotoreceptor retinoid-binding protein antibody|Interstitial retinol binding protein antibody|Interstitial retinol-binding protein antibody|IRBP antibody|RBP 3 antibody|rbp3 antibody|RBPI antibody|RET3_HUMAN antibody|Retinol binding protein 3 antibody|Retinol binding protein 3 interstitial antibody|Retinol-binding protein 3 antibody|Anti-RBP3 antibody (ab173492)

SCBT cat No: sc-18598|

Name

Rabbit polyclonal RBP3 antibody

Catalogue No.

A6403

Reactivity

Human

Immunogen

Recombinant protein of human RBP3

Host

Rabbit

Applications

WB, IHC, IF

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200
IF 1:50 – 1:100

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 135kDa/Observed: Refer to Figures

Formulation

RBP3 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

RBP3 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

IRBP antibody, RBPI antibody, RP66 antibody, D10S64 antibody, D10S65 antibody, D10S66 antibody

Database links

Human UniProt/Swiss-Prot:P10745

Protein names

IRBP, RBPI, RP66, D10S64, D10S65, D10S66

Protein function

IRBP shuttles 11-cis and all trans retinoids between the retinol isomerase in the pigment epithelium and the visual pigments in the photoreceptor cells of the retina.

Protein sequence and domain

Belongs to the peptidase S41A family.

Protein cellular localization

Secreted, extracellular space, extracellular matrix, interphotoreceptor matrix. Note: Interphotoreceptor matrix that permeates the space between the retina and the contiguous layer of pigment epithelium cells.

Background

Interphotoreceptor retinol-binding protein is a large glycoprotein known to bind retinoids and found primarily in the interphotoreceptor matrix of the retina between the retinal pigment epithelium and the photoreceptor cells. It is thought to transport retinoids between the retinal pigment epithelium and the photoreceptors, a critical role in the visual process.The human IRBP gene is approximately 9.5 kbp in length and consists of four exons separated by three introns. The introns are 1.6-1.9 kbp long. The gene is transcribed by photoreceptor and retinoblastoma cells into an approximately 4.3-kilobase mRNA that is translated and processed into a glycosylated protein of 135,000 Da. The amino acid sequence of human IRBP can be divided into four contiguous homology domains with 33-38% identity, suggesting a series of gene duplication events. In the gene, the boundaries of these domains are not defined by exon-intron junctions, as might have been expected. The first three homology domains and part of the fourth are all encoded by the first large exon, which is 3,180 base pairs long. The remainder of the fourth domain is encoded in the last three exons, which are 191, 143, and approximately 740 base pairs long, respectively.

Note

AntibodyPlus can customize RBP3 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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