Rabbit polyclonal RGS7 antibody (A6720)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal RGS7 antibody (A6720)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

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OTTHUMP00000037994 antibody|Regulator of G protein signalling 7 antibody|Regulator of G-protein signaling 7 antibody|Regulator of G-protein signaling RGS7 antibody|Regulator of G-protein signalling 7 antibody|Anti-RGS7 antibody (ab88643)

SCBT cat No: sc-398222|sc-271643|sc-28836|sc-8141|sc-8139|

Name

Rabbit polyclonal RGS7 antibody

Catalogue No.

A6720

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human RGS7

Host

Rabbit

Applications

WB, IHC

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 57kDa/Observed: Refer to figures

Formulation

RGS7 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

RGS7 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Database links

Human UniProt/Swiss-Prot:P49802

Protein function

Regulates G protein-coupled receptor signaling cascades. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form . The RGS7/GNB5 dimer enhances GNAO1 GTPase activity . May play a role in synaptic vesicle exocytosis . Modulates the activity of potassium channels that are activated by GNAO1 in response to muscarinic acetylcholine receptor M2/CHRM2 signaling .

Protein sequence and domain

Contains 1 DEP domain.; Contains 1 G protein gamma domain.; Contains 1 RGS domain.

Protein post-translational modifications

Palmitoylated.; Ubiquitinated, leading to rapid proteasomal degradation.; Phosphorylation and subsequent interaction with 14-3-3 proteins inhibits GAP activity.

Protein cellular localization

Cytoplasm, cytosol . Cytoplasm . Cell membrane . Membrane ; Peripheral membrane protein ; Cytoplasmic side . Note: Interaction with PKD1 promotes location at the cell membrane . Interaction with RGS7BP promotes location at the cell membrane .

Research area

All research areas>Signaling Intermediates>RGS
(View all antibody categories related to Signaling Intermediates)

Note

AntibodyPlus can customize RGS7 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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