Rabbit polyclonal RNF5 antibody (A8351)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal RNF5 antibody (A8351)

Supplier: ABclonal Inc.

Recommended applications: WB

Recommended dilution:

WB 1:500 – 1:2000

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

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RMA1 antibody, RING5 antibody
E3 ubiquitin protein ligase RNF5 antibody|E3 ubiquitin-protein ligase RNF5 antibody|G16 antibody|HsRma1 antibody|NG2 antibody|OTTHUMP00000029107 antibody|Protein G16 antibody|Ram1 homolog antibody|RING finger protein 5 antibody|RING5 antibody|RMA1 antibody|RNF 5 antibody|RNF5 antibody|RNF5_HUMAN antibody|Anti-RNF5 antibody – N-terminal (ab200389)

SCBT cat No: sc-81716|sc-169211|

Name

Rabbit polyclonal RNF5 antibody

Catalogue No.

A8351

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human RNF5

Host

Rabbit

Applications

WB

Recommended dilution

WB 1:500 – 1:2000

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 20kDa/Observed: Refer to figures

Formulation

RNF5 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

RNF5 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

RMA1 antibody, RING5 antibody

Database links

Human UniProt/Swiss-Prot:Q99942

Protein names

RMA1, RING5

Protein function

Has E2-dependent E3 ubiquitin-protein ligase activity. May function together with E2 ubiquitin-conjugating enzymes UBE2D1/UBCH5A and UBE2D2/UBC4. Mediates ubiquitination of PXN/paxillin and Salmonella type III secreted protein sopA. May be involved in regulation of cell motility and localization of PXN/paxillin. Mediates the ‘Lys-63’-linked polyubiquitination of JKAMP thereby regulating JKAMP function by decreasing its association with components of the proteasome and ERAD; the ubiquitination appears to involve E2 ubiquitin-conjugating enzyme UBE2N. Mediates the ‘Lys-48’-linked polyubiquitination of TMEM173 at ‘Lys-150’ leading to its proteasomal degradation; the ubiquitination occurrs in mitochondria after viral transfection and regulates antiviral responses.

Protein tissue specificity

Widely expressed.

Protein sequence and domain

Contains 1 RING-type zinc finger.

Protein cellular localization

Membrane; Multi-pass membrane protein. Mitochondrion membrane. Endoplasmic reticulum membrane. Note: Predominantly located in the plasma membrane, with some localization occurring within cytoplasmic organelles.

Background

The protein encoded by this gene contains a RING finger, which is a motif known to be involved in protein-protein interactions. This protein is a membrane-bound ubiquitin ligase. It can regulate cell motility by targeting paxillin ubiquitination and altering the distribution and localization of paxillin in cytoplasm and cell focal adhesions.

Research area

All research areas>Transcription Regulators>RNF
(View all antibody categories related to Transcription Regulators)

Note

AntibodyPlus can customize RNF5 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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